Background and main text Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is
a complex and controversial clinical condition without having established causative factors …

Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

Exosomes are small membrane vesicles (ranging from 30 nm to 150 nm), secreted by
different cell types upon fusion of multivesicular bodies (MVB) to the cell plasma membrane …

Human cytomegalovirus (HCMV) has evolved sophisticated immune evasion mechanisms
that target both the innate and adaptive immune responses. However, how HCMV encoded …

Recently, viruses have been shown to regulate selective autophagy for productive
infections. For instance, human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma …

Hemochorial placentas have evolved defense mechanisms to prevent the vertical
transmission of viruses to the immunologically underdeveloped fetus. Unlike somatic cells …

Viral control of mitochondrial quality and content has emerged as an important mechanism
for counteracting the host response to virus infection. Despite the knowledge of this crucial …

Mitochondria support multiple cell functions, but an accumulation of dysfunctional or
excessive mitochondria is detrimental to cells. We previously demonstrated that a defect in …

Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that
target cellular IRFs and/or other innate-immune and stress signaling regulators and …

Gammaherpesviruses are ubiquitous pathogens that establish lifelong infections in the vast
majority of adults worldwide. Importantly, these viruses are associated with numerous …