Antimicrobial peptides in 2014

G Wang, B Mishra, K Lau, T Lushnikova, R Golla… - Pharmaceuticals, 2015 - mdpi.com
This article highlights new members, novel mechanisms of action, new functions, and
interesting applications of antimicrobial peptides reported in 2014. As of December 2014 …

Challenges and Complications of Poly(lactic-co-glycolic acid)-Based Long-Acting Drug Product Development

YW Lim, WS Tan, KL Ho, AR Mariatulqabtiah… - Pharmaceutics, 2022 - mdpi.com
Poly (lactic-co-glycolic acid)(PLGA) is one of the preferred polymeric inactive ingredients for
long-acting parenteral drug products that are constituted of complex formulations. Despite …

Silicon and glass very large scale microfluidic droplet integration for terascale generation of polymer microparticles

S Yadavali, HH Jeong, D Lee, D Issadore - Nature communications, 2018 - nature.com
Microfluidic chips can generate emulsions, which can be used to synthesize polymer
microparticles that have superior pharmacological performance compared to particles …

Microfluidic assisted synthesis of PLGA drug delivery systems

S Rezvantalab, MK Moraveji - RSC advances, 2019 - pubs.rsc.org
Poly (lactic-co-glycolic acid)(PLGA) is a biocompatible and biodegradable polymer that
recently attracted attention for use as part of drug delivery systems (DDS). In this context …

Monodisperse CaCO3-loaded gelatin microspheres for reversing lactic acid-induced chemotherapy resistance during TACE treatment

M Chen, X Guo, L Shen, J Ding, J Yu, X Chen… - International journal of …, 2023 - Elsevier
Transarterial chemoembolization (TACE) is an important approach for the treatment of
unresectable hepatocellular carcinoma (HCC). However, the lactic acid-induced acidic …

Approaches to improve therapeutic efficacy of biodegradable PLA/PLGA microspheres: a review

SL Bee, ZAA Hamid, M Mariatti, BH Yahaya… - Polymer …, 2018 - Taylor & Francis
This review aims to provide a comprehensive overview about various innovative strategies
that have been employed by recent researchers to overcome with the shortcomings …

Structured biodegradable polymeric microparticles for drug delivery produced using flow focusing glass microfluidic devices

EE Ekanem, SA Nabavi… - ACS applied materials …, 2015 - ACS Publications
Biodegradable poly (dl-lactic acid)(PLA) and poly (lactic-co-glycolic acid)(PLGA)
microparticles with tunable size, shape, internal structure and surface morphology were …

Microfluidic preparation of PLGA composite microspheres with mesoporous silica nanoparticles for finely manipulated drug release

J Zhou, Y Zhai, J Xu, T Zhou, L Cen - International Journal of Pharmaceutics, 2021 - Elsevier
The current study explored the feasibility of a microfluidic preparation of PLGA composite
microspheres with mesoporous silica nanoparticles (MSNs) to finely manipulate the drug …

Meeting the unmet: from traditional to cutting-edge techniques for poly lactide and poly lactide-co-glycolide microparticle manufacturing

A Schoubben, M Ricci, S Giovagnoli - Journal of Pharmaceutical …, 2019 - Springer
Background Polylactides (PLA) and poly lactide-co-glycolides (PLGA) undoubtedly are
among the major drivers in the pharmaceutical market. Their relevance in pharmaceutics …

Synergistic effects of doxorubicin PLGA nanoparticles and simvastatin loaded in silk films for local treatment of breast cancer

A Rakhshani, S Maghsoudian, H Motasadizadeh… - Journal of Drug Delivery …, 2025 - Elsevier
An encouraging strategy to address challenges in breast cancer treatment is local drug
delivery, targeting the primary tumor site to minimize side effects and drug resistance …