NAD+ was discovered during yeast fermentation, and since its discovery, its important roles
in redox metabolism, aging, and longevity, the immune system and DNA repair have been …

Cancer cells have a unique energy metabolism for sustaining rapid proliferation. The
preference for anaerobic glycolysis under normal oxygen conditions is a unique trait of …

Purpose: Colorectal cancer is the second most common cancer in women and the third most
common in men worldwide. However, despite current progress, many patients with …

Tumor cells have increased requirements for NAD+. Thus, many cancers exhibit an
increased reliance on NAD+ production pathways. This dependence may be exploited …

Nicotinamide adenine dinucleotide (NAD) is an essential redox cofactor, but it also acts as a
substrate for NAD-consuming enzymes, regulating cellular events such as DNA repair and …

Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme for various
physiological processes including energy metabolism, DNA repair, cell growth, and cell …

NAD+ is an important metabolite in cell homeostasis that acts as an essential cofactor in
oxidation–reduction (redox) reactions in various energy production processes, such as the …

The increasing incidence of thyroid cancer (TC) cannot be fully explained by overdiagnosis.
Metabolic syndrome (Met S) is highly prevalent due to the modern lifestyle, which can lead …

Gliomas are the most prevalent primary malignant brain tumors associated with poor
prognosis. NAMPT, a rate-limiting enzyme that boosts the nicotinamide adenine …

Skeletal muscle enables posture, breathing, and locomotion. Skeletal muscle also impacts
systemic processes such as metabolism, thermoregulation, and immunity. Skeletal muscle is …