Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …

Naringin and naringenin are the main bioactive polyphenols in citrus fruits, the consumption
of which is beneficial for human health and has been practiced since ancient times …

Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Flavonoids are widely distributed as secondary metabolites produced by plants and play
important roles in plant physiology, having a variety of potential biological benefits such as …

Great interest is currently centered on the biologic activities of quercetin a polyphenol
belonging to the class of flavonoids, natural products well known for their beneficial effects …

Mitochondrial targeting is a promising approach for solving current issues in clinical
application of chemotherapy and diagnosis of several disorders. Here, we discuss direct …

Over the years, coronaviruses (CoV) have posed a severe public health threat, causing an
increase in mortality and morbidity rates throughout the world. The recent outbreak of a …

In aging and neurodegenerative diseases, loss of distinct type of neurons characterizes
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …

The anticancer effects of polyphenols are ascribed to several signaling pathways including
the tumor suppressor gene tumor protein 53 (p53). Expression of endogenous p53 is silent …

Chlorogenic acid (CGA) decreases colon cancer-cell proliferation but the combined anti-
cancer effects of CGA with its major colonic microbial metabolites, caffeic acid (CA), 3 …