Nature exhibits rapid evolution in response to human activities. When using natural resources for their own profit, humans should account for such responses. Stackelberg …
A Bukkuri, JS Brown - Methods in Ecology and Evolution, 2023 - Wiley Online Library
State‐structured populations are ubiquitous in biology, from the age‐structure of animal societies to the life cycles of parasitic species. Understanding how this structure contributes …
Evolvability is the capacity of a population to generate heritable variation that can be acted upon by natural selection. This ability influences the adaptations and fitness of individual …
The polyaneuploid cancer cell (PACC) state promotes cancer lethality by contributing to survival in extreme conditions and metastasis. Recent experimental evidence suggests that …
VD Ao, DV Tran, KT Pham, DM Nguyen, HD Tran… - Quantum …, 2023 - mdpi.com
We establish an analogy between the Fokker–Planck equation describing evolutionary landscape dynamics and the Schrödinger equation which characterizes quantum …
A Bukkuri, KJ Pienta, I Hockett, RH Austin… - Medical Oncology, 2023 - Springer
In this didactic paper, we present a theoretical modeling framework, called the G-function, that integrates both the ecology and evolution of cancer to understand oncogenesis. The G …
A Bukkuri - Theory in Biosciences, 2024 - Springer
Mathematical models of cancer and bacterial evolution have generally stemmed from a gene-centric framework, assuming clonal evolution via acquisition of resistance-conferring …
A Bukkuri, FR Adler - Evolution, Medicine, and Public Health, 2023 - academic.oup.com
Abstract Background and Objectives Cancer biomarkers provide information on the characteristics and extent of cancer progression and help inform clinical decision-making …
A Bukkuri - Theory in Biosciences, 2024 - Springer
Understanding the ecological and evolutionary dynamics of populations is critical for both basic and applied purposes in a variety of biological contexts. Although several modeling …