Green synthesis of gold nanoparticles using plant extracts as beneficial prospect for cancer theranostics

KK Bharadwaj, B Rabha, S Pati, T Sarkar… - Molecules, 2021 - mdpi.com
Gold nanoparticles (AuNPs) have been widely explored and are well-known for their
medical applications. Chemical and physical synthesis methods are a way to make AuNPs …

Apoptosis regulation in the penumbra after ischemic stroke: expression of pro-and antiapoptotic proteins

AB Uzdensky - Apoptosis, 2019 - Springer
Ischemic stroke is the leading cause of human disability and mortality in the world. The main
problem in stroke therapy is the search of efficient neuroprotector capable to rescue neurons …

Full-coverage regulations of autophagy by ROS: from induction to maturation

J Zhou, XY Li, YJ Liu, J Feng, Y Wu, HM Shen, GD Lu - Autophagy, 2022 - Taylor & Francis
Macroautophagy/autophagy is an evolutionarily well-conserved recycling process in
response to stress conditions, including a burst of reactive oxygen species (ROS) …

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

J Yu, S Li, J Qi, Z Chen, Y Wu, J Guo, K Wang… - Cell death & …, 2019 - nature.com
Pyroptosis, a form of programmed cell death (PCD), has garnered increasing attention as it
relates to innate immunity and diseases. However, the involvement of pyroptosis in the …

AMPK, mitochondrial function, and cardiovascular disease

S Wu, MH Zou - International journal of molecular sciences, 2020 - mdpi.com
Adenosine monophosphate-activated protein kinase (AMPK) is in charge of numerous
catabolic and anabolic signaling pathways to sustain appropriate intracellular adenosine …

Arsenic contamination of groundwater: a review of sources, prevalence, health risks, and strategies for mitigation

S Shankar, U Shanker, Shikha - The scientific world journal, 2014 - Wiley Online Library
Arsenic contamination of groundwater in different parts of the world is an outcome of natural
and/or anthropogenic sources, leading to adverse effects on human health and ecosystem …

Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions

R Marullo, E Werner, N Degtyareva, B Moore… - PloS one, 2013 - journals.plos.org
Cisplatin is one of the most effective and widely used anticancer agents for the treatment of
several types of tumors. The cytotoxic effect of cisplatin is thought to be mediated primarily …

The complex interplay between mitochondria, ROS and entire cellular metabolism

AV Kuznetsov, R Margreiter, MJ Ausserlechner… - Antioxidants, 2022 - mdpi.com
Besides their main function for energy production in form of ATP in processes of oxidative
phosphorylation (OxPhos), mitochondria perform many other important cellular functions …

Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century

WH Lee, CY Loo, M Bebawy, F Luk… - Current …, 2013 - ingentaconnect.com
Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is
widely used in Southeast Asia, China and India in food preparation and for medicinal …

Role of c-Jun N-terminal kinase (JNK) in obesity and type 2 diabetes

JHM Yung, A Giacca - Cells, 2020 - mdpi.com
Obesity has been described as a global epidemic and is a low-grade chronic inflammatory
disease that arises as a consequence of energy imbalance. Obesity increases the risk of …