Age-related macular degeneration (AMD) is a chronic and progressive degenerative
disease of the retina, which culminates in blindness and affects mainly the elderly …

Age‐related macular degeneration (AMD) is a progressive degenerative disease that is the
leading cause of vision loss in the elderly population. Degeneration/dysregulation of the …

Ocular inflammation is a defining feature of sight threating diseases and its dysregulation
can catalyze and or propagate ocular neurodegenerative maladies such as age-related …

For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

Increased intraocular pressure (IOP) represents a major risk factor for glaucoma, a prevalent
eye disease characterized by death of retinal ganglion cells; lowering IOP is the only proven …

Age-related macular degeneration (AMD) is a leading cause of blindness. Genetic variants
at the chromosome 1q31. 3 encompassing the complement factor H (CFH, FH) and CFH …

The complement system is involved in the pathogenesis of several ocular diseases,
providing a rationale for the investigation of complement-targeting therapeutics for these …

Diabetic retinopathy (DR) is a microvascular complication of diabetes and is the leading
cause of vision loss in working-age adults. Recent studies have implicated the complement …

The choroid is a key player in maintaining ocular homeostasis and plays a role in a variety of
chorioretinal diseases, many of which are poorly understood. Recent advances in the field of …

Age-related macular degeneration (AMD) remains a major cause of legal blindness, and
treatment for the geographic atrophy form of AMD is a significant unmet need. Dysregulation …