D Vuckovic - Analytical and bioanalytical chemistry, 2012 - Springer
The choice of sample-preparation method is extremely important in metabolomic studies because it affects both the observed metabolite content and biological interpretation of the …
SL Cramer, A Saha, J Liu, S Tadi, S Tiziani, W Yan… - Nature medicine, 2017 - nature.com
Cancer cells experience higher oxidative stress from reactive oxygen species (ROS) than do non-malignant cells because of genetic alterations and abnormal growth; as a result …
N Psychogios, DD Hau, J Peng, AC Guo, R Mandal… - PloS one, 2011 - journals.plos.org
Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest …
Metabolomics is the discipline where endogenous and exogenous metabolites are assessed, identified and quantified in different biological samples. Metabolites are crucial …
Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have become methods of choice to characterize the human metabolome and MS-based …
Y Simón-Manso, MS Lowenthal, LE Kilpatrick… - Analytical …, 2013 - ACS Publications
Recent progress in metabolomics and the development of increasingly sensitive analytical techniques have renewed interest in global profiling, ie, semiquantitative monitoring of all …
Metabolomics is a dynamic and emerging research field, similar to proteomics, transcriptomics and genomics in affording global understanding of biological systems. It is …
The field of metabolomics continues to witness rapid growth driven by fundamental studies, methods development, and applications in a number of disciplines that include biomedical …
Abstract 1 H NMR spectra from urine can yield information-rich data sets that offer important insights into many biological and biochemical phenomena. However, the quality and utility …