Brain organoids are self‐organized, three‐dimensional (3D) aggregates derived from
pluripotent stem cells that have cell types and cellular architectures resembling those of the …

Engineered three-dimensional (3D) in vitro and ex vivo neural tissues, also known as “mini
brains and spinal cords in a dish,” can be derived from different types of human stem cells …

The emerging technology of brain organoids deriving from human pluripotent stem cells
provides unprecedented opportunities to study human brain development and associated …

The human brain is a complicated and precisely organized organ. Exogenous chemicals,
such as pollutants, drugs, and industrial chemicals, may affect the biological processes of …

Autism spectrum disorders (ASDs) are a set of disorders characterised by social and
communication deficits caused by numerous genetic lesions affecting brain development …

Recent advances in molecular and cellular engineering, such as human cell
reprogramming, genome editing, and patient-specific organoids, have provided …

Over the past decade, tremendous progress has been made in defining autism spectrum
disorder (ASD) as a disorder of brain connectivity. Indeed, whole-brain imaging studies …

Pediatric bipolar disorder (PBD) is a severe mood dysregulation condition that affects 0.5–
1% of children and teens in the United States. It is associated with recurrent episodes of …

Abstract Pediatric Bipolar Disorder (PBD) is a severe mood dysregulation condition
experienced by 0.5–1% of children and teens in the United States. It is associated with …