Lidocaine tripotassium phosphate complex laden microemulsion for prolonged local anaesthesia: In vitro and in vivo studies

FA Maulvi, LV Pillai, KP Patel, AR Desai… - Colloids and Surfaces B …, 2020 - Elsevier
Lidocaine is widely used as a local anaesthetic in the clinical practice to manage pre-and
post-operative pain, skin burns, etc. However, the short duration of action (< 2 h) of marketed …

Stability‐indicating HPLC method for acyclovir and lidocaine in topical formulations

V Mulabagal, M Annaji, S Kurapati… - Biomedical …, 2020 - Wiley Online Library
A simple, rapid and accurate stability‐indicating HPLC assay was developed for the
determination of acyclovir and lidocaine in topical formulations. Chromatographic separation …

HPLC-DAD stability indicating determination of nitrofurazone and lidocaine hydrochloride in their combined topical dosage form

RA Shaalan, TS Belal - Journal of chromatographic science, 2010 - academic.oup.com
In this work, a simple, rapid, and selective high-performance liquid chromatography (HPLC)
method with diode array detection was developed for the simultaneous determination of …

Gradient HPLC-DAD stability indicating determination of miconazole nitrate and lidocaine hydrochloride in their combined oral gel dosage form

TS Belal, RS Haggag - Journal of chromatographic science, 2012 - academic.oup.com
The pharmaceutical combination of miconazole nitrate (MZ) and lidocaine hydrochloride
(LD) is used in the curative and prophylactic therapy of the oral and gastro-intestinal …

Decoupling of conductivity relaxation from structural relaxation in protic ionic liquids and general properties

Z Wojnarowska, K Kołodziejczyk, KJ Paluch… - Physical Chemistry …, 2013 - pubs.rsc.org
The main focus of this work is the study of conductivity relaxation of amorphous lidocaine
hemisuccinate near the glass transition at ambient pressure. Measurements have been …

Sustained delivery of prilocaine and lidocaine using depot microemulsion system: in vitro, ex vivo and in vivo animal studies

X Zhang, M Dang, W Zhang, Y Lei… - Drug development and …, 2020 - Taylor & Francis
Topical drug delivery for local anesthetics has been an interesting area of research for
formulators considering the resistance and barrier properties of skin and high clearance rate …

Automated analysis of lidocaine and its metabolite in plasma by in‐tube solid‐phase microextraction coupled with LC‐UV for pharmacokinetic study

JA Caris, BJG Silva, ECD Moisés… - Journal of separation …, 2012 - Wiley Online Library
A sensitive, selective, and reproducible in‐tube solid‐phase microextraction and liquid
chromatographic (in‐tube SPME/LC‐UV) method for determination of lidocaine and its …

[PDF][PDF] Functionalized hydroxyapatite scaffolds coated with sodium alginate and chitosan for controlled drug delivery

A Dubnika, D Loca, L Berzina-Cimdina - Proceedings of the Estonian …, 2012 - vana.kirj.ee
Due to its bioactivity, hydroxyapatite (HAp) is one of the most perspective materials for
controlled drug delivery. Biodegradable polymers like chitosan and sodium alginate are …

An isocratic RP-HPLC-UV method for simultaneous quantification of tizanidine and lidocaine: application to in vitro release studies of a subcutaneous implant

CJ Picco, QK Anjani, RF Donnelly, E Larrañeta - Analytical Methods, 2024 - pubs.rsc.org
Implantable devices have been widely investigated to improve the treatment of multiple
diseases. Even with low drug loadings, these devices can achieve effective delivery and …

[PDF][PDF] Extraction-spectrophotometric determination of lidocaine hydrochloride in pharmaceuticals

LS Omer, RJ Ali - Int. J. Chem, 2017 - pdfs.semanticscholar.org
Simple, selective and highly detectable spectrophotometric method has been developed
and validated for the determination of Lidocaine hydrochloride in standard and commercial …