[HTML][HTML] Anticancer peptide: Physicochemical property, functional aspect and trend in clinical application

W Chiangjong… - International …, 2020 - build.spandidos-publications.com
Cancer is currently ineffectively treated using therapeutic drugs, and is also able to resist
drug action, resulting in increased side effects following drug treatment. A novel therapeutic …

Peptide‐based therapeutic cancer vaccine: current trends in clinical application

W Liu, H Tang, L Li, X Wang, Z Yu, J Li - Cell Proliferation, 2021 - Wiley Online Library
The peptide‐based therapeutic cancer vaccines have attracted enormous attention in recent
years as one of the effective treatments of tumour immunotherapy. Most of peptide‐based …

[HTML][HTML] Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients

MS Block, AB Dietz, MP Gustafson, KR Kalli… - Nature …, 2020 - nature.com
In ovarian cancer (OC), IL-17-producing T cells (Th17s) predict improved survival, whereas
regulatory T cells predict poorer survival. We previously developed a vaccine whereby …

Facts and hopes in immunotherapy of endometrial cancer

JA Marín-Jiménez, S García-Mulero, X Matías-Guiu… - Clinical Cancer …, 2022 - AACR
Immunotherapy with checkpoint inhibitors has changed the paradigm of treatment for many
tumors, and endometrial carcinoma is not an exception. Approved treatment options are …

[HTML][HTML] Bioactive peptides for anticancer therapies

Y Zhang, C Wang, W Zhang, X Li - Biomaterials Translational, 2023 - ncbi.nlm.nih.gov
Cancer is a serious concern in public health worldwide. Numerous modalities including
surgery, radiotherapy, and chemotherapy, have been used for cancer therapies in clinic …

Advances in immunotherapy for gynecological Malignancies

M Tu, J Xu - Critical reviews in oncology/hematology, 2023 - Elsevier
To date, surgery, chemotherapy and radiotherapy are mainly used to treat or remove
gynecological malignancies. However, these approaches have their limitations when facing …

[HTML][HTML] Immunotherapy in endometrial cancer: rationale, practice and perspectives

W Cao, X Ma, JV Fischer, C Sun, B Kong, Q Zhang - Biomarker Research, 2021 - Springer
Tumor immunotherapy has attracted more and more attention nowadays, and multiple
clinical trials have confirmed its effect in a variety of solid tumors. Immune checkpoint …

Recent advances in using folate receptor 1 (FOLR1) for cancer diagnosis and treatment, with an emphasis on cancers that affect women

P Varaganti, V Buddolla, BA Lakshmi, YJ Kim - Life Sciences, 2023 - Elsevier
A glycosylphosphatidylinositol (GPI)-anchored glycoprotein called the folate receptor 1
(FOLR1) facilitates the transportation of folate by mediating receptor-mediated endocytosis …

[HTML][HTML] Barriers to immunotherapy in ovarian cancer: metabolic, genomic, and immune perturbations in the tumour microenvironment

RL Johnson, M Cummings, A Thangavelu… - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy hinges on stimulating patients' immune system to fight
cancer. This treatment has led to improved survival in patients with malignancies such as …

[HTML][HTML] Therapeutic strategies targeting folate receptor α for ovarian cancer

J Mai, L Wu, L Yang, T Sun, X Liu, R Yin… - Frontiers in …, 2023 - frontiersin.org
Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and presents a major
clinical challenge due to limited treatment options. Folate receptor alpha (FRα), encoded by …