The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …

Background: During the height of the global COVID-19 pandemic, the test-negative design
(TND) was extensively used in many countries to evaluate COVID-19 vaccine effectiveness …

Background: Monkeypox, a viral zoonotic disease, is causing a global outbreak outside of
endemic areas. Objective: To characterize the outbreak of monkeypox in Montréal, the first …

Given limited supply of approved vaccines and constrained medical resources, design of a
vaccination strategy to control a pandemic is an economic problem. We use time-series and …

Background A major goal of coronavirus disease 2019 (COVID-19) vaccination is to prevent
severe outcomes (hospitalizations and deaths). We estimated the effectiveness of …

Comparison of the Test-negative Design and Cohort Design Wit... : Epidemiology
Comparison of the Test-negative Design and Cohort Design With Explicit Target Trial …

Although numerous COVID-19 vaccines are effective against COVID-19 infection and
variants of concern (VOC) in the real world, it is imperative to obtain evidence of the …

Current vaccines against COVID-19 elicit immune responses that are overall strong but
wane rapidly. As a consequence, the necessary booster shots have contributed to vaccine …

Background The objective of this study was to test the hypothesis that subsequent doses of
the coronavirus disease 2019 (COVID-19) vaccine are associated with lower incidence of …

Background As the COVID-19 pandemic continues and new variants such as Omicron
emerge, we aimed to re-evaluate vaccine effectiveness as well as impacts of rigorously …