Validating MRI-Derived Myocardial Stiffness Estimates Using In Vitro Synthetic Heart Models

FO Kolawole, M Peirlinck, TE Cork… - Annals of Biomedical …, 2023 - Springer
Impaired cardiac filling in response to increased passive myocardial stiffness contributes to
the pathophysiology of heart failure. By leveraging cardiac MRI data and ventricular …

Estimating cardiomyofiber strain in vivo by solving a computational model

LE Perotti, IA Verzhbinsky, K Moulin, TE Cork… - Medical image …, 2021 - Elsevier
Since heart contraction results from the electrically activated contraction of millions of
cardiomyocytes, a measure of cardiomyocyte shortening mechanistically underlies cardiac …

Ventricular helix angle trends and long-range connectivity

AJ Wilson, QJ Han, LE Perotti, DB Ennis - International Conference on …, 2023 - Springer
Abstract Porcine hearts (N= 14) underwent ex vivo diffusion tensor imaging (DTI) at 3T. DTI
analysis showed regional differences in helix angle (HA) range. The HA range in the …

A groupwise registration and tractography framework for cardiac myofiber architecture description by diffusion MRI: an application to the ventricular junctions

J Magat, M Yon, Y Bihan-Poudec, V Ozenne - Plos one, 2022 - journals.plos.org
Background Knowledge of the normal myocardial–myocyte orientation could theoretically
allow the definition of relevant quantitative biomarkers in clinical routine to diagnose heart …

Diffusion biomarkers in chronic myocardial infarction

T Rahman, K Moulin, DB Ennis, LE Perotti - International Conference on …, 2021 - Springer
Cardiac diffusion tensor magnetic resonance imaging (cDTI) allows estimating the
aggregate cardiomyocyte architecture in healthy subjects and its remodeling as a result of …

Cardiac Diffusion Tensor Biomarkers of Chronic Infarction Based on In Vivo Data

T Rahman, K Moulin, LE Perotti - Applied Sciences, 2022 - mdpi.com
In vivo cardiac diffusion tensor imaging (cDTI) data were acquired in swine subjects six to
ten weeks post-myocardial infarction (MI) to identify microstructural-based biomarkers of MI …

Check for updates

D Trend, L Mujezin¹, A Salkić… - 32nd Scientific-Expert …, 2023 - books.google.com
Nutrition that is based on mostly consuming plant origin food, also known as plant-based
diet, generates multiple forms of dietary patterns, which in common have lower …

System for Validating MRI-based Myocardial Stiffness Estimation Techniques Using 3D-Printed Heart Phantoms

FO Kolawole, TE Cork, M Loecher, J Zimmermann… - archive.ismrm.org
Cardiac MRI and finite element based techniques can be used to obtain subject-specific
myocardial material properties. Verifying the accuracy and precision of these techniques …

Diffusion Biomarkers to Characterize Tissue Microstructure in Chronic Myocardial Infarction

MT Rahman - 2021 - stars.library.ucf.edu
Non-invasive imaging techniques to detect and characterize infarcted myocardium are
critical for myocardial infarction (MI) prognosis and post-MI risk assessment. Many existing …

Impact of cardiac geometry segmentation on MRI-driven estimates of myocardial stiffness in an in vitro synthetic heart model

F Kolawole, M Peirlinck, TE Cork, ME Levenston… - archive.ismrm.org
MRI-driven computational constitutive modeling can be used to obtain subject-specific
myocardial passive stiffness. Verifying the accuracy and precision of this technique requires …