Radiation therapy‐associated toxicity: Etiology, management, and prevention

K Wang, JE Tepper - CA: a cancer journal for clinicians, 2021 - Wiley Online Library
Radiation therapy (RT) is a curative treatment for many malignancies and provides effective
palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT …

Consensuses, controversies, and future directions in treatment deintensification for human papillomavirus‐associated oropharyngeal cancer

JJ Kang, Y Yu, L Chen, K Zakeri… - CA: a cancer journal …, 2023 - Wiley Online Library
The most common cancer caused by human papillomavirus (HPV) infection in the United
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …

NCCN Guidelines® insights: Head and neck cancers, version 1.2022: Featured updates to the NCCN guidelines

JJ Caudell, ML Gillison, E Maghami, S Spencer… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity
(including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer …

Plasma circulating tumor HPV DNA for the surveillance of cancer recurrence in HPV-associated oropharyngeal cancer

BS Chera, S Kumar, C Shen, R Amdur… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Plasma circulating tumor human papillomavirus DNA (ctHPVDNA) is a sensitive
and specific biomarker of human papillomavirus (HPV)-associated oropharyngeal …

Evaluation of substantial reduction in elective radiotherapy dose and field in patients with human papillomavirus–associated oropharyngeal carcinoma treated with …

CJ Tsai, SM McBride, N Riaz, JJ Kang… - JAMA …, 2022 - jamanetwork.com
Importance Several de-escalation strategies for human papillomavirus (HPV)–associated
oropharyngeal carcinoma (OPC) have focused on deintensifying gross disease treatment …

Optimizing treatment de‐escalation in head and neck cancer: current and future perspectives

AJ Rosenberg, EE Vokes - The oncologist, 2021 - academic.oup.com
Abstract Treatment of locoregionally advanced head and neck squamous cell carcinoma
involves a multidisciplinary approach that combines surgery, radiotherapy, and systemic …

Hypoxia-directed treatment of human papillomavirus–related oropharyngeal carcinoma

NY Lee, EJ Sherman, HK Schöder, R Wray… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Standard curative-intent chemoradiotherapy for human papillomavirus (HPV)–
related oropharyngeal carcinoma results in significant toxicity. Since hypoxic tumors are …

Negative predictive value of circulating tumor tissue modified viral (TTMV)-HPV DNA for HPV-driven oropharyngeal cancer surveillance

GJ Hanna, SA Roof, J Jabalee, EM Rettig… - Clinical Cancer …, 2023 - AACR
Purpose: Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell
carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in …

[HTML][HTML] HPV and head and neck cancers: Towards early diagnosis and prevention

L Galati, S Chiocca, D Duca, M Tagliabue… - Tumour Virus …, 2022 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide with an increasing trend of its incidence. Alcohol consumption, smoking, and viral …

A review on curability of cancers: more efforts for novel therapeutic options are needed

S Wang, Y Liu, Y Feng, J Zhang, J Swinnen, Y Li, Y Ni - Cancers, 2019 - mdpi.com
Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …