Transcriptional and post-transcriptional gene regulation by long non-coding RNA

IM Dykes, C Emanueli - Genomics, Proteomics and …, 2017 - academic.oup.com
Advances in genomics technology over recent years have led to the surprising discovery
that the genome is far more pervasively transcribed than was previously appreciated. Much …

MicroRNA-155: a master regulator of inflammation

G Mahesh, R Biswas - Journal of Interferon & Cytokine Research, 2019 - liebertpub.com
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …

MiR-155: an important regulator of neuroinflammation

VD Zingale, A Gugliandolo, E Mazzon - International Journal of Molecular …, 2021 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression
at the post-transcriptional level and that play an important role in many cellular processes …

Biogenesis of small RNAs in animals

VN Kim, J Han, MC Siomi - Nature reviews Molecular cell biology, 2009 - nature.com
Small RNAs of 20–30 nucleotides can target both chromatin and transcripts, and thereby
keep both the genome and the transcriptome under extensive surveillance. Recent progress …

MicroRNA genes are transcribed by RNA polymerase II

Y Lee, M Kim, J Han, KH Yeom, S Lee, SH Baek… - The EMBO …, 2004 - embopress.org
MicroRNAs (miRNAs) constitute a large family of noncoding RNAs that function as guide
molecules in diverse gene silencing pathways. Current efforts are focused on the regulatory …

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

GA Calin, C Sevignani, CD Dumitru… - Proceedings of the …, 2004 - National Acad Sciences
A large number of tiny noncoding RNAs have been cloned and named microRNAs (miRs).
Recently, we have reported that miR-15a and miR-16a, located at 13q14, are frequently …

[HTML][HTML] Identification of tissue-specific microRNAs from mouse

M Lagos-Quintana, R Rauhut, A Yalcin, J Meyer… - Current biology, 2002 - cell.com
MicroRNAs (miRNAs) are a new class of noncoding RNAs, which are encoded as short
inverted repeats in the genomes of invertebrates and vertebrates [1, 2]. It is believed that …

[HTML][HTML] microRNAs as oncogenes and tumor suppressors

B Zhang, X Pan, GP Cobb, TA Anderson - Developmental biology, 2007 - Elsevier
microRNAs (miRNAs) are a new class of non-protein-coding, endogenous, small RNAs.
They are important regulatory molecules in animals and plants. miRNA regulates gene …

[HTML][HTML] RAS is regulated by the let-7 microRNA family

SM Johnson, H Grosshans, J Shingara, M Byrom… - Cell, 2005 - cell.com
MicroRNAs (miRNAs) are regulatory RNAs found in multicellular eukaryotes, including
humans, where they are implicated in cancer. The let-7 miRNA times seam cell terminal …

Regulation of the MIR155 host gene in physiological and pathological processes

TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …