Metabolic pathways and redox reactions are at the core of life. In the past decade (s),
numerous discoveries have shed light on how metabolic pathways determine the cellular …

Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such
protection is mediated, in large part, by two main B cell memory 'walls'—namely, long-lived …

Following infection or vaccination, activated B cells at extrafollicular sites or within germinal
centers (GCs) undergo vigorous clonal proliferation. Proliferating lymphocytes have been …

Metabolic reprogramming in cancer and immune cells occurs to support their increasing
energy needs in biological tissues. Here we propose Single Cell Spatially resolved …

Store-operated Ca2+ entry (SOCE) is a ubiquitous Ca2+ signaling pathway that is
evolutionarily conserved across eukaryotes. SOCE is triggered physiologically when the …

Aerobic organisms need to maintain cellular redox homeostasis. Glutathione peroxidase-4
(Gpx4) has the unique ability to protect cells against lipid peroxidation. Here, we show that …

Epstein-Barr virus (EBV) is a human tumor virus which preferentially infects resting human B
cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent …

Molecular carcinogenesis is a multistep process that involves acquired abnormalities in key
biological processes. The complexity of cancer pathogenesis is best illustrated in the six …

Hypoxia is a common hallmark of healthy tissues in physiological states or chronically
inflamed tissues in pathological states. Mammalian cells sense and adapt to hypoxia mainly …

The edible and medicinal plants (EMPs) are becoming an abundant source for cancer
prevention and treatment since the natural and healthy trend for modern human beings …