The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …

Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

Indoles constitute extensively explored heterocyclic ring systems with wide range of
applications in pathophysiological conditions that is, cancer, microbial and viral infections …

Bacterial infections are account for the majority of hospital-acquired and community-
acquired infections. The emergency and widespread of drug-resistant pathogens has further …

Thiazolidinone is considered as a biologically important active scaffold that possesses
almost all types of biological activities. Successful introduction of ralitoline as a potent anti …

The features of the chemistry of 4-thiazolidinone and pyrazole/pyrazolines as
pharmacologically attractive scaffolds were described in a number of reviews in which the …

Abstract A series of 3‐[(1H‐pyrazol‐3‐yl) imino] indolin‐2‐one derivatives were designed
using the molecular hybridization method, characterized using different spectroscopic …

The catalytic nucleophilic substitution of tertiary alcohols using carbon or heteroatom based
nucleophiles is a versatile methodology for the efficient, diverse and atom economical …

In the face of escalating challenges of microbial resistance strains, this study describes the
design and synthesis of 5‐({1‐[(1H‐1, 2, 3‐triazol‐4‐yl) methyl]‐1H‐indol‐3‐yl} methylene) …

Objective The spirooxindole heterocyclic scaffold is found in many natural products and has
been identified as an important bioactive agent. Background Over the past few decades …