Hope for CKD-MBD patients: new diagnostic approaches for better treatment of CKD-MBD
B Hocher, A Pasch - Kidney Diseases, 2017 - karger.com
Background: Chronic kidney disease-mineral and bone disorder (CKD-MBD) patients have
a huge morbidity and mortality. Only relatively minor progress in therapeutic strategies has …
a huge morbidity and mortality. Only relatively minor progress in therapeutic strategies has …
Nasal administration and plasma pharmacokinetics of parathyroid hormone peptide PTH 1-34 for the treatment of osteoporosis
RG Pearson, T Masud, E Blackshaw, A Naylor… - Pharmaceutics, 2019 - mdpi.com
Nasal delivery of large peptides such as parathyroid 1-34 (PTH 1-34) can benefit from a
permeation enhancer to promote absorption across the nasal mucosa into the bloodstream …
permeation enhancer to promote absorption across the nasal mucosa into the bloodstream …
Ectopic osteogenesis by type I collagen loaded with a novel synthesized PTH‐related peptide‐1 in vivo
Y Wang, J Wang, J Zheng, M Yu, L Cai… - … Research Part A, 2020 - Wiley Online Library
This study aims to investigate the ability of parathyroid hormone (PTH)‐related peptide‐
1/type I collagen (PTHrP‐1/Col‐I) scaffold material to induce ectopic osteogenesis in the …
1/type I collagen (PTHrP‐1/Col‐I) scaffold material to induce ectopic osteogenesis in the …
Why current PTH assays mislead clinical decision making in patients with secondary hyperparathyroidism
B Hocher, L Yin - Nephron, 2017 - karger.com
Preclinical studies in cell culture systems as well as in whole animal chronic kidney disease
(CKD) models showed that parathyroid hormone (PTH), oxidized at the 2 methionine …
(CKD) models showed that parathyroid hormone (PTH), oxidized at the 2 methionine …
Preclinical development of EXT608, an investigational parathyroid hormone derivative with extended half-life for the treatment of hypoparathyroidism
DB Hall, CH Kostyla, LM Hales, TM Soliman - JBMR plus, 2024 - academic.oup.com
Hypoparathyroidism, a deficiency of parathyroid hormone (PTH), results in hypocalcemia,
hyperphosphatemia, and hypercalciuria. The disease is poorly controlled by calcium and …
hyperphosphatemia, and hypercalciuria. The disease is poorly controlled by calcium and …
Need for better PTH assays for clinical research and patient treatment
B Hocher, S Zeng - Clinical Chemistry and Laboratory Medicine …, 2018 - degruyter.com
Parathyroid hormone (PTH)–a 84-amino acids containing peptide hormone secreted by the
parathyroid gland–regulates the blood calcium level via GPCR binding and subsequent …
parathyroid gland–regulates the blood calcium level via GPCR binding and subsequent …
Rekombinant yöntemlerle sentetik parathormon üretimi
Z Dişçi - 2017 - openaccess.bezmialem.edu.tr
Proteins have a great importance within the field of biotechnologically derived products.
Synthetically produced proteins using recombinant methods are produced for therapeutic …
Synthetically produced proteins using recombinant methods are produced for therapeutic …