The interaction between depression and stroke is highly complex. Post‐stroke depression
(PSD) is among the most frequent neuropsychiatric consequences of stroke. Depression …

Two of the most common and incapacitating mental health disorders around the world are
major depressive disorder (MDD) and post-stroke depression (PSD). MDD is thought to …

Quetiapine is an atypical antipsychotic drug that is also US FDA approved for treating
bipolar depression, albeit by an unknown mechanism. To discover the potential mechanism …

The chronic stress model was developed on the basis of the stress–diathesis hypothesis of
depression. However, these behavioural responses associated with different stress …

The unpredictable chronic mild stress (UCMS) model was developed based upon the stress-
diathesis hypothesis of depression. Most effects of UCMS can be reversed by …

Selective serotonin re-uptake inhibitors (SSRI) have been widely used in treatment of major
depression because of their efficacy, safety, and tolerability. Escitalopram, an SSRI, is …

Global cerebral ischemia (GCI) commonly occurs in the elderly. Subcortical white matter
lesions and oligodendrocyte (OLG) loss caused by cerebral ischemia have been implicated …

The present study examined the behavioral and neurohistological changes induced by the
bilateral common carotid artery occlusion (BCCAO) model of brain ischemia in Swiss mice …

AIM: The present study has been designed to explore the nitric oxide mechanism in the
protective effect of naringin against I/R induced neurobehavioral alterations, oxidative …

Stroke is one of the most frequent causes of death and disability worldwide causing a major
clinical and socioeconomic impact. Although the pathophysiology of brain ischemia and …