Integration site selection by retroviruses and transposable elements in eukaryotes

T Sultana, A Zamborlini, G Cristofari… - Nature Reviews …, 2017 - nature.com
Transposable elements and retroviruses are found in most genomes, can be pathogenic
and are widely used as gene-delivery and functional genomics tools. Exploring whether …

Retroviral DNA integration

P Lesbats, AN Engelman, P Cherepanov - Chemical reviews, 2016 - ACS Publications
The integration of a DNA copy of the viral RNA genome into host chromatin is the defining
step of retroviral replication. This enzymatic process is catalyzed by the virus-encoded …

De novo resveratrol production through modular engineering of an Escherichia coliSaccharomyces cerevisiae co-culture

SF Yuan, X Yi, TG Johnston, HS Alper - Microbial cell factories, 2020 - Springer
Background Resveratrol is a plant secondary metabolite with diverse, potential health-
promoting benefits. Due to its nutraceutical merit, bioproduction of resveratrol via microbial …

The endoplasmic reticulum unfolded protein response–homeostasis, cell death and evolution in virus infections

V Prasad, UF Greber - FEMS microbiology reviews, 2021 - academic.oup.com
Viruses elicit cell and organismic stress, and offset homeostasis. They trigger intrinsic, innate
and adaptive immune responses, which limit infection. Viruses restore homeostasis by …

Truth in wine yeast

R Gonzalez, P Morales - Microbial Biotechnology, 2022 - Wiley Online Library
Evolutionary history and early association with anthropogenic environments have made
Saccharomyces cerevisiae the quintessential wine yeast. This species typically dominates …

Viral reverse transcriptases

L Menéndez-Arias, A Sebastián-Martín, M Álvarez - Virus research, 2017 - Elsevier
Reverse transcriptases (RTs) play a major role in the replication of Retroviridae,
Metaviridae, Pseudoviridae, Hepadnaviridae and Caulimoviridae. RTs are enzymes that are …

Sequence Assembly of Yarrowia lipolytica Strain W29/CLIB89 Shows Transposable Element Diversity

C Magnan, J Yu, I Chang, E Jahn, Y Kanomata, J Wu… - PloS one, 2016 - journals.plos.org
Yarrowia lipolytica, an oleaginous yeast, is capable of accumulating significant cellular mass
in lipid making it an important source of biosustainable hydrocarbon-based chemicals. In …

Engineered yeast for efficient de novo synthesis of 7‐dehydrocholesterol

L Qu, X Xiu, G Sun, C Zhang, H Yang… - Biotechnology and …, 2022 - Wiley Online Library
The synthesis of vitamin D3 precursor 7‐dehydrocholesterol (7‐DHC) by microbial
fermentation has much attracted attention owing to its advantages of environmental …

Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements

L Qi, Y Sui, XX Tang, RJ McGinty, XZ Liang… - PLoS …, 2023 - journals.plos.org
Although homologous recombination between transposable elements can drive genomic
evolution in yeast by facilitating chromosomal rearrangements, the details of the underlying …

A Cas12a‐based gene editing system for Phytophthora infestans reveals monoallelic expression of an elicitor

AMV Ah‐Fong, AM Boyd, MEH Matson… - Molecular plant …, 2021 - Wiley Online Library
Phytophthora infestans is a destructive pathogen of potato and a model for investigations of
oomycete biology. The successful application of a CRISPR gene editing system to P …