Radioresistance of non-small cell lung cancers and therapeutic perspectives

M Césaire, J Montanari, H Curcio, D Lerouge… - Cancers, 2022 - mdpi.com
Simple Summary The poor survival of unresectable locally advanced stage non-small cell
lung cancer is due to the resistance to chemoradiotherapy and local/distant relapses …

Current treatments for non-small cell lung cancer

Q Guo, L Liu, Z Chen, Y Fan, Y Zhou, Z Yuan… - Frontiers in …, 2022 - frontiersin.org
Despite improved methods of diagnosis and the development of different treatments,
mortality from lung cancer remains surprisingly high. Non-small cell lung cancer (NSCLC) …

In vivo liquid biopsy for glioblastoma malignancy by the AFM and LSPR based sensing of exosomal CD44 and CD133 in a mouse model

A Thakur, C Xu, WK Li, G Qiu, B He, SP Ng… - Biosensors and …, 2021 - Elsevier
Glioblastoma (GBM) is the fatal brain tumor in which secreted lactate enhances the
expression of cluster of differentiation 44 (CD44) and the release of exosomes, cell-derived …

Resveratrol suppresses lung cancer by targeting cancer stem-like cells and regulating tumor microenvironment

C Xie, C Liang, R Wang, K Yi, X Zhou, X Li… - The Journal of …, 2023 - Elsevier
Increasing evidence indicate that cancer stem cells (CSCs) are the key driver of tumor
initiation and recurrence. The cellular and soluble components of the tumor …

[HTML][HTML] A novel C-terminal heat shock protein 90 inhibitor that overcomes STAT3-Wnt-β-catenin signaling-mediated drug resistance and adverse effects

HJ Lee, HY Min, YS Yong, J Ann, CT Nguyen, MT La… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: The heat shock protein (Hsp) system plays important roles in cancer stem cell
(CSC) and non-CSC populations. However, limited efficacy due to drug resistance and …

Weighted gene coexpression network analysis of features that control cancer stem cells reveals prognostic biomarkers in lung adenocarcinoma

Y Liao, Y Wang, M Cheng, C Huang, X Fan - Frontiers in Genetics, 2020 - frontiersin.org
Purpose We aimed to identify new prognostic biomarkers of lung adenocarcinoma (LUAD)
based on cancer stem cell theory. Materials and Methods: RNA-seq and microarray data …

[HTML][HTML] Cannabidiol induces cell death in human lung cancer cells and cancer stem cells

H Hamad, BB Olsen - Pharmaceuticals, 2021 - mdpi.com
Pharmaceuticals | Free Full-Text | Cannabidiol Induces Cell Death in Human Lung Cancer
Cells and Cancer Stem Cells Next Article in Journal Novel DYRK1A Inhibitor Rescues …

Glutamine metabolism in cancer stem cells: a complex liaison in the tumor microenvironment

F Pacifico, A Leonardi, E Crescenzi - International Journal of Molecular …, 2023 - mdpi.com
In this review we focus on the role of glutamine in control of cancer stem cell (CSC) fate. We
first provide an overview of glutamine metabolism, and then summarize relevant studies …

Regulation and functions of α6-integrin (CD49f) in Cancer biology

R Khademi, H Malekzadeh, S Bahrami, N Saki… - Cancers, 2023 - mdpi.com
Simple Summary Integrins play key roles in mediating cell adhesion and delivering chemical
and mechanical signals to the interior of the cell. Consequently, they actively control cellular …

Nanomedicine strategies for management of drug resistance in lung cancer

M Haider, A Elsherbeny, V Pittalà, V Consoli… - International Journal of …, 2022 - mdpi.com
Lung cancer (LC) is one of the leading causes of cancer occurrence and mortality
worldwide. Treatment of patients with advanced and metastatic LC presents a significant …