Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering

S Eskandari, T Guerin, I Toth, RJ Stephenson - Advanced drug delivery …, 2017 - Elsevier
Self-assembled peptides have shown outstanding characteristics for vaccine delivery and
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …

Peptide fibrillization

IW Hamley - Angewandte Chemie International Edition, 2007 - Wiley Online Library
The fibrillization of peptides is relevant to many diseases based on the deposition of
amyloids. The formation of fibrils is being intensively studied, especially in terms of …

Integrating Computation, Experiment, and Machine Learning in the Design of Peptide‐Based Supramolecular Materials and Systems

M Ramakrishnan, A van Teijlingen… - Angewandte Chemie …, 2023 - Wiley Online Library
Interest in peptide‐based supramolecular materials has grown extensively since the 1980s
and the application of computational methods has paralleled this. These methods contribute …

Self-assembling peptides: From design to biomedical applications

S La Manna, C Di Natale, V Onesto… - International journal of …, 2021 - mdpi.com
Self-assembling peptides could be considered a novel class of agents able to harvest an
array of micro/nanostructures that are highly attractive in the biomedical field. By modifying …

Short to ultrashort peptide-based hydrogels as a platform for biomedical applications

N Yadav, MK Chauhan, VS Chauhan - Biomaterials science, 2020 - pubs.rsc.org
Short peptides have attracted significant attention from researchers in the past few years due
to their easy design, synthesis and characterization, diverse functionalisation possibilities …

Peptide hydrogels–versatile matrices for 3D cell culture in cancer medicine

P Worthington, DJ Pochan, SA Langhans - Frontiers in oncology, 2015 - frontiersin.org
Traditional two-dimensional (2D) cell culture systems have contributed tremendously to our
understanding of cancer biology but have significant limitations in mimicking in vivo …

Peptide sequence determines structural sensitivity to supramolecular polymerization pathways and bioactivity

SC Yuan, JA Lewis, H Sai, SJ Weigand… - Journal of the …, 2022 - ACS Publications
Pathways in supramolecular polymerization traverse different regions of the system's energy
landscape, affecting not only their architectures and internal structure but also their …

Revisiting thioflavin T (ThT) fluorescence as a marker of protein fibrillation–The prominent role of electrostatic interactions

E Arad, H Green, R Jelinek, H Rapaport - Journal of colloid and interface …, 2020 - Elsevier
Thioflavin T (ThT), a benzothiazole-based fluorophore, is a prominent dye widely employed
for monitoring amyloid fibril assembly. Despite the near-universal presumption that ThT …

Self-assembly and gelation properties of α-helix versus β-sheet forming peptides

A Saiani, A Mohammed, H Frielinghaus, R Collins… - Soft Matter, 2009 - pubs.rsc.org
We have investigated the self-assembly and gelation properties of a set of four octa-
peptides: AEAEAKAK, AEAKAEAK, FEFEFKFK and FEFKFEFK. The phenylalanine based …

Self-assembly of ionic-complementary peptides: a physicochemical viewpoint

P Chen - Colloids and Surfaces A: Physicochemical and …, 2005 - Elsevier
A major focus in the current development in nanotechnology and biotechnology is to find
suitable molecular materials that are amenable to engineering design. Self-assembling …