Antiinflammatory action of glucocorticoids—new mechanisms for old drugs

T Rhen, JA Cidlowski - New England Journal of Medicine, 2005 - Mass Medical Soc
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Nitric oxide signaling in brain function, dysfunction, and dementia

JR Steinert, T Chernova, ID Forsythe - The Neuroscientist, 2010 - journals.sagepub.com
Nitric oxide (NO) is an important signaling molecule that is widely used in the nervous
system. With recognition of its roles in synaptic plasticity (long-term potentiation, LTP; long …

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock

L Liu, Y Yan, M Zeng, J Zhang, MA Hanes, G Ahearn… - Cell, 2004 - cell.com
The current perspective of NO biology is formulated predominantly from studies of NO
synthesis. The role of S-nitrosothiol (SNO) formation and turnover in governing NO-related …

Nitric oxide and the vascular endothelium

S Moncada, EA Higgs - The vascular endothelium I, 2006 - Springer
The vascular endothelium synthesises the vasodilator and anti-aggregatory mediator nitric
oxide (NO) from L-arginine. This action is catalysed by the action of NO synthases, of which …

Reactive oxygen species in hypertension: an update

B Lassègue, KK Griendling - American journal of hypertension, 2004 - academic.oup.com
Hypertension is associated with an elevation of reactive oxygen species (ROS) and
frequently also with an impairment of endogenous antioxidant mechanisms. Experimental …

[HTML][HTML] Role of nitric oxide in placental vascular development and function

BJ Krause, MA Hanson, P Casanello - Placenta, 2011 - Elsevier
Nitric oxide (NO) is one of the most pleiotropic signaling molecules at systemic and cellular
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …

Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression

CS Facemire, AB Nixon, R Griffiths, H Hurwitz… - …, 2009 - Am Heart Assoc
Drugs and antibodies that interrupt vascular endothelial growth factor (VEGF) signaling
pathways improve outcomes in patients with a variety of cancers by inhibiting tumor …

Alterations in endothelial nitric oxide synthase activity and their relevance to blood pressure

T Suvorava, S Metry, S Pick, G Kojda - Biochemical pharmacology, 2022 - Elsevier
Among all physiologic functions of nitric oxide (NO) known so far, NO-dependent regulation
of vascular tone is one of the most important. Under physiological conditions vascular NO is …

Toxoplasmosis: a pathway to neuropsychiatric disorders

S Tyebji, S Seizova, AJ Hannan, CJ Tonkin - … & Biobehavioral Reviews, 2019 - Elsevier
Toxoplasma gondii is an obligate intracellular parasite that resides, in a latent form, in the
human central nervous system. Infection with Toxoplasma drastically alters the behaviour of …

Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome?

E Nisoli, E Clementi, MO Carruba… - Circulation research, 2007 - Am Heart Assoc
The metabolic syndrome is a group of risk factors of metabolic origin that are accompanied
by increased risk for type 2 diabetes mellitus and cardiovascular disease. These risk factors …