Network-based approaches for multi-omics integration

G Zhou, S Li, J Xia - Computational methods and data analysis for …, 2020 - Springer
Network-based approach is rapidly emerging as a promising strategy to integrate and
interpret different-omics datasets, including metabolomics. The first section of this chapter …

Systems biology of gastric cancer: perspectives on the omics-based diagnosis and treatment

XJ Shi, Y Wei, B Ji - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
Gastric cancer is the fifth most diagnosed cancer in the world, affecting more than a million
people and causing nearly 783,000 deaths each year. The prognosis of advanced gastric …

LncRNA LINC00319 is associated with tumorigenesis and poor prognosis in glioma

Q Li, Q Wu, Z Li, Y Hu, F Zhou, Z Zhai, S Yue… - European journal of …, 2019 - Elsevier
Glioma is one of the most universally diagnosed malignant tumors in the central nervous
system with high mortality and morbidity in the world. Long non-coding long intergenic non …

Identification of circRNA biomarker for gastric cancer through integrated analysis

MT Hossain, S Li, MS Reza, S Feng… - Frontiers in Molecular …, 2022 - frontiersin.org
Gastric cancer (GC) is one of the most common malignant tumors and ranks third in cancer
mortality globally. Although, a lot of advancements have been made in diagnosis and …

Identification of hub pathways and drug candidates in gastric cancer through systems biology

SR Salarikia, M Kashkooli, MJ Taghipour… - Scientific Reports, 2022 - nature.com
Gastric cancer is the fourth cause of cancer death globally, and gastric adenocarcinoma is
its most common type. Efforts for the treatment of gastric cancer have increased its median …

A systems biology approach to pathogenesis of gastric cancer: gene network modeling and pathway analysis

N Mottaghi-Dastjerdi, A Ghorbani, H Montazeri… - BMC …, 2023 - Springer
Background Gastric cancer (GC) ranks among the most common malignancies worldwide.
This study aimed to find critical genes/pathways in GC pathogenesis. Methods Gene …

Knockdown of LINC00511 promotes radiosensitivity of thyroid carcinoma cells via suppressing JAK2/STAT3 signaling pathway

Y Chen, C Bao, X Zhang, X Lin, Y Fu - Cancer Biology & Therapy, 2019 - Taylor & Francis
Thyroid carcinoma is the most widespread malignancy in endocrine system with the
increasing incidence. Despite of the advanced approaches to the management of thyroid …

RETRACTED ARTICLE: Silencing of long non-coding RNA XIST represses gastric cancer progression through blocking NFκB pathway via inhibiting HNF4A-mediated …

P Li, L Wang, P Li, F Hu, Y Cao, D Tang, G Ye… - Cancer Gene …, 2021 - nature.com
Gastric cancer (GC) is a common cancer and a leading cause of cancer-related deaths
worldwide. Recent studies have supported the important role of long non-coding RNAs …

Systems biology and biomarkers in necrotizing soft tissue infections

E Saccenti, M Svensson - Necrotizing Soft Tissue Infections: Clinical and …, 2020 - Springer
In necrotizing soft tissue infection (NSTI) there is a need to identify biomarker sets that can
be used for diagnosis and disease management. The INFECT study was designed to obtain …

Identification of potential inhibitors for drug resistance in acute lymphoblastic leukemia through differentially expressed gene analysis and in silico screening

B Özay, EY Tükel, GA Duran, Y Kiraz - Analytical Biochemistry, 2024 - Elsevier
Acute lymphoblastic leukemia (ALL) is a disease of lymphocyte origin predominantly
diagnosed in children. While its 5-year survival rate is high, resistance to chemotherapy …