Isoquercitrin: Pharmacology, toxicology, and metabolism

K Valentová, J Vrba, M Bancířová, J Ulrichová… - Food and Chemical …, 2014 - Elsevier
Abstract The flavonoid isoquercitrin (quercetin-3-O-β-d-glucopyranoside) is commonly found
in medicinal herbs, fruits, vegetables and plant-derived foods and beverages. This article …

Evolution, human-microbe interactions, and life history plasticity

G Rook, F Bäckhed, BR Levin, MJ McFall-Ngai… - The Lancet, 2017 - thelancet.com
A bacterium was once a component of the ancestor of all eukaryotic cells, and much of the
human genome originated in microorganisms. Today, all vertebrates harbour large …

Food, immunity, and the microbiome

H Tilg, AR Moschen - Gastroenterology, 2015 - Elsevier
There is increasing evidence that ingested diet-borne components are involved in the
pathogenesis of disorders such as inflammatory bowel diseases, atherosclerosis, and type 2 …

[HTML][HTML] Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promoting resilience to stress-induced anxiety-and depressive-like …

S Westfall, F Caracci, D Zhao, Q Wu, T Frolinger… - Brain, behavior, and …, 2021 - Elsevier
Chronic stress disrupts immune homeostasis while gut microbiota-derived metabolites
attenuate inflammation, thus promoting resilience to stress-induced immune and behavioral …

The aryl hydrocarbon receptor in barrier organ physiology, immunology, and toxicology

C Esser, A Rannug, Q Ma - Pharmacological reviews, 2015 - Elsevier
The aryl hydrocarbon receptor (AhR) is an evolutionarily old transcription factor belonging to
the Per-ARNT-Sim–basic helix-loop-helix protein family. AhR translocates into the nucleus …

[HTML][HTML] Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation

CJG Pinto, MÁ Ávila-Gálvez, Y Lian, P Moura-Alves… - Redox Biology, 2023 - Elsevier
Abstract The Aryl Hydrocarbon Receptor (AHR) is a ligand-dependent transcription factor
able to control complex transcriptional processes in several cell types, which has been …

Galangin activates Nrf2 signaling and attenuates oxidative damage, inflammation, and apoptosis in a rat model of cyclophosphamide-induced hepatotoxicity

SH Aladaileh, MH Abukhalil, SAM Saghir, H Hanieh… - Biomolecules, 2019 - mdpi.com
Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …

Can plant phenolic compounds protect the skin from airborne particulate matter?

YC Boo - Antioxidants, 2019 - mdpi.com
The skin is directly exposed to the polluted atmospheric environment, and skin diseases,
such as atopic dermatitis and acne vulgaris, can be induced or exacerbated by airborne …

Polyphenolic phytochemicals in cancer prevention and therapy: bioavailability versus bioefficacy

JM Estrela, S Mena, E Obrador… - Journal of medicinal …, 2017 - ACS Publications
Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …

Role of AhR/ARNT system in skin homeostasis

M Furue, M Takahara, T Nakahara, H Uchi - Archives of Dermatological …, 2014 - Springer
Aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that binds to
structurally diverse synthetic and naturally occurring chemicals including dioxins, flavonoids …