Effects of Feeding Milk Replacer Ad Libitum or in Restricted Amounts for the First Five Weeks of Life on the Growth, Metabolic Adaptation, and Immune Status of …

CT Schäff, J Gruse, J Maciej, M Mielenz, E Wirthgen… - PLoS …, 2016 - journals.plos.org
The pre-weaning period is critical for calf health and growth, and intensive milk feeding
programs may assist postnatal development by improving body growth and organ …

[HTML][HTML] Analysis of the IGF-system in milk from farm animals–Occurrence, regulation, and biomarker potential

Z Meyer, C Höflich, E Wirthgen, S Olm… - Growth Hormone & IGF …, 2017 - Elsevier
IGFs and IGF-binding proteins (IGFBPs) are abundantly present in milk and in dairy
products. Compared to the IGFs, the IGFBP have received less attention in milk, although …

[HTML][HTML] Influence of ad libitum milk replacer feeding and butyrate supplementation on the systemic and hepatic insulin-like growth factor I and its binding proteins in …

D Frieten, C Gerbert, C Koch, G Dusel, K Eder… - Journal of Dairy …, 2018 - Elsevier
Ad libitum milk feeding and butyrate (B) supplementation have the potential to stimulate
postnatal growth and development in calves. The somatotropic axis is the main endocrine …

Methylating micronutrient supplementation during pregnancy influences foetal hepatic gene expression and IGF signalling and increases foetal weight

M Oster, W Nuchchanart, N Trakooljul, E Murani… - European journal of …, 2016 - Springer
Purpose Maternal diet during pregnancy impacts foetal growth and development. In
particular, dietary levels of methylating micronutrients (methionine, folate, choline, vitamins …

Modulation of growth hormone receptor-insulin-like growth factor 1 axis by dietary protein in young ruminants

CS Firmenich, N Schnepel, K Hansen… - British journal of …, 2020 - cambridge.org
A reduced protein intake causes a decrease in insulin-like growth factor 1 (IGF1)
concentrations and modulates Ca homoeostasis in young goats. IGF1 is synthesised by the …

[HTML][HTML] Effects of colostrum instead of formula feeding for the first 2 days postnatum on whole-body energy metabolism and its endocrine control in neonatal calves

W Liermann, CT Schäff, J Gruse, M Derno… - Journal of dairy …, 2020 - Elsevier
Colostrum provides high amounts of nutritive and non-nutritive substrates, which are
essential for calf nutrition and passive immunization. Colostral growth factors and hormones …

[HTML][HTML] Antepartal insulin-like growth factor 1 and insulin-like growth factor binding protein 2 concentrations are indicative of ketosis in dairy cows

M Piechotta, W Mysegades, U Ligges, J Lilienthal… - Journal of dairy …, 2015 - Elsevier
A study involving a small number of cows found that the concentrations of insulin-like growth
hormone 1 (IGF1) may be a useful predictor of metabolic disease. Further, IGF1 may provide …

Increased concentrations of insulin-like growth factor binding protein (IGFBP)-2, IGFBP-3, and IGFBP-4 are associated with fetal mortality in pregnant cows

K Mense, J Heidekorn-Dettmer, E Wirthgen… - Frontiers in …, 2018 - frontiersin.org
Insulin-like growth factors (IGFs) play a critical role in fetal growth, and components of the
IGF system have been associated with fetal growth restriction in women. In human …

[HTML][HTML] Effects of a combined essential fatty acid and conjugated linoleic acid abomasal infusion on metabolic and endocrine traits, including the somatotropic axis, in …

S Haubold, C Kröger-Koch, A Tuchscherer… - Journal of dairy …, 2020 - Elsevier
The objective of this study was to test the effects of essential fatty acids (EFA), particularly α-
linolenic acid (ALA), and conjugated linoleic acid (CLA) supplementation on metabolic and …

[HTML][HTML] Quantitative Western ligand blotting reveals common patterns and differential features of IGFBP-fingerprints in domestic ruminant breeds and species

E Wirthgen, C Höflich, M Spitschak, C Helmer… - Growth Hormone & IGF …, 2016 - Elsevier
The insulin-like growth factor binding proteins (IGFBPs) are determinants of local IGF-effects
and thus have an impact on growth and metabolism in vertebrate species. In farm animals …