The self-assembly of proteins is an essential process for a variety of cellular functions
including cell respiration, mobility and division. On the other hand, protein or peptide …

Protein misfolding is a general hallmark of protein deposition diseases, such as Alzheimer's
disease or Parkinson's disease, in which different types of aggregated species (oligomers …

The self-assembly of α-synuclein (αS) into intraneuronal inclusion bodies is a key
characteristic of Parkinson's disease. To define the nature of the species giving rise to …

α-Synuclein amyloid aggregation is a defining molecular feature of Parkinson's disease,
Lewy body dementia, and multiple system atrophy, but can also be found in other …

Amyloid fibril formation plays a central role in the pathogenesis of a number of
neurodegenerative diseases, including Alzheimer and Parkinson diseases. Transient …

Pathogenic α-synuclein (α-syn) is a prion-like protein that drives the pathogenesis of Lewy
Body Dementia (LBD) and Parkinson's Disease (PD). To target pathogenic α-syn preformed …

Increasing evidence suggests that the process of alpha‐synuclein (α‐syn) aggregation from
monomers into amyloid fibrils and Lewy bodies, via oligomeric intermediates plays an …

Abstract After Alzheimer's disease, Parkinson's disease is the most frequent
neurodegenerative disorder. Although numerous treatments have been developed to control …

Ensembles of protein aggregates are characterized by a nano-and micro-scale
heterogeneity of the species. This diversity translates into a variety of effects that protein …

The pathological hallmark of Parkinson's disease (PD) is Lewy bodies that form within the
brain from aggregated forms of α‐synuclein (α‐syn). These toxic α‐syn aggregates are …