Deep sequencing has been revolutionizing biology and medicine in recent years, providing
single base‐level precision for our understanding of nucleic acid sequences in high …

The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …

Although gene fusions have been recognized as important drivers of cancer for decades,
our understanding of the prevalence and function of gene fusions has been revolutionized …

We developed an innovative hybrid sequencing approach, IDP-fusion, to detect fusion
genes, determine fusion sites and identify and quantify fusion isoforms. IDP-fusion is the first …

Background Transcripts, which have been subject to Post-transcriptional exon shuffling
(PTES), have an exon order inconsistent with the underlying genomic sequence. These …

Wheat yield is greatly reduced because of the occurrence of leaf spot diseases. Bipolaris
sorokiniana is the main pathogenic fungus in leaf spot disease. In this study, B. sorokiniana …

Background Agarwood is a traditional Chinese medicine used as a clinical sedative,
carminative, and antiemetic drug. Agarwood is formed in Aquilaria sinensis when A. sinensis …

Evolutionary medicine, which integrates evolutionary biology and medicine, significantly
enhances our understanding of human traits and disease susceptibility. However, previous …

Gene fusions play a critical role in some cancers and can serve as important clinical targets.
In epithelial ovarian cancer (EOC), the contribution of fusions, especially by histological type …

Identification of fusion gene is of prominent importance in cancer research field because of
their potential as carcinogenic drivers. RNA sequencing (RNA-Seq) data have been the …