Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood

HS Lee - Nutrients, 2015 - mdpi.com
Exposure to environmental factors in early life can influence developmental processes and
long-term health in humans. Early life nutrition and maternal diet are well-known examples …

[HTML][HTML] Focus: Addiction: Back by popular demand: A narrative review on the history of food addiction research

A Meule - The Yale journal of biology and medicine, 2015 - ncbi.nlm.nih.gov
In recent years, the concept of food addiction has gained more and more popularity. This
approach acknowledges the apparent parallels between substance use disorders and …

Epigenetic germline inheritance of diet-induced obesity and insulin resistance

P Huypens, S Sass, M Wu, D Dyckhoff, M Tschöp… - Nature …, 2016 - nature.com
There is considerable controversy regarding epigenetic inheritance in mammalian gametes.
Using in vitro fertilization to ensure exclusive inheritance via the gametes, we show that a …

Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations

UD Wankhade, Y Zhong, P Kang, M Alfaro… - PloS one, 2017 - journals.plos.org
Objective Non-alcoholic fatty liver disease (NAFLD) is an important co-morbidity associated
with obesity and a precursor to steatohepatitis. However, the contributions of gestational and …

Circadian rhythms in diet-induced obesity

A Engin - Obesity and lipotoxicity, 2017 - Springer
The biological clocks of the circadian timing system coordinate cellular and physiological
processes and synchronizes these with daily cycles, feeding patterns also regulates …

Maternal obesity, maternal overnutrition and fetal programming: effects of epigenetic mechanisms on the development of metabolic disorders

E Şanlı, S Kabaran - Current genomics, 2019 - ingentaconnect.com
Background: Maternal obesity and maternal overnutrition, can lead to epigenetic alterations
during pregnancy and these alterations can influence fetal and neonatal phenotype which …

Effects of maternal obesity on fetal programming: molecular approaches

C Neri, AG Edlow - Cold Spring Harbor …, 2016 - perspectivesinmedicine.cshlp.org
Maternal obesity has become a worldwide epidemic. Obesity and a high-fat diet have been
shown to have deleterious effects on fetal programming, predisposing offspring to adverse …

Head to Head Comparison of Short-Term Treatment with the NAD+ Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice

GM Uddin, NA Youngson, DA Sinclair… - Frontiers in …, 2016 - frontiersin.org
Obesity is well known to be a major cause of several chronic metabolic diseases, which can
be partially counteracted by exercise. This is due, in part, to an upregulation of mitochondrial …

Food additives, food and the concept of 'food addiction': is stimulation of the brain reward circuit by food sufficient to trigger addiction?

AY Onaolapo, OJ Onaolapo - Pathophysiology, 2018 - Elsevier
In the last few years, the concept of 'food addiction'has continued to gain popularity, with
human and animal studies demonstrating the differential effects of foods that are high in fat …

Misalignment of circadian rhythms in diet-induced obesity

A Engin - Obesity and Lipotoxicity, 2024 - Springer
The biological clocks of the circadian timing system coordinate cellular and physiological
processes and synchronize them with daily cycles. While the central clock in the …