Extracellular vesicles (EVs) are nano-sized membrane-bounded particles, released by all
cells and capable of transporting bioactive cargoes, proteins, lipids, and nucleic acids, to …

An increasing number of men require long-term drug therapy for various diseases. However,
the effects of long-term drug therapy on male fertility are often not well evaluated in clinical …

Aims This study aimed to explore the effect of epididymosomes on the proliferative efficiency
of spermatogonial stem cells (SSCs) in vitro and the resumption of spermatogenesis in the …

Spermatogenesis is a highly complicated biological process that occurs in the epithelium of
the seminiferous tubules. It is regulated by a complex network of endocrine and paracrine …

Abstract Background Small extracellular vesicles (EVs), exemplified by exosomes, mediate
intercellular communication by transporting proteins, mRNAs, and miRNAs. Post …

Spermatogonial stem cells (SSCs) play a crucial role in the male reproductive system,
responsible for maintaining continuous spermatogenesis. The microenvironment or niche of …

Exosomes are a subset of Extracellular vesicles (EVs) released by most cells in the body
and can play a significant role in the intercellular connection. Researchers today claim that …

Exosomes (Exos), belonging to extracellular vesicles, are cell‐derived nano‐sized vesicles
with the potential to carry different kinds of biological molecules. Many studies have proved …

Significance: In recent decades, male fertility has been severely reduced worldwide. The
causes underlying this decline are multifactorial, and include, among others, genetic …

Background Spermatogenesis is a fundamental process crucial for male reproductive health
and fertility. Exosomes, small membranous vesicles released by various cell types, have …