In a worldwide effort to generate clinically useful therapeutic or preventive interventions,
harnessing biophysical stimuli for directing cell fate is a powerful strategy. With the vision to …

The study of cell migration on biomaterials is of great significance in tissue engineering and
regenerative medicine. In recent years, there has been increasing evidence that the physical …

The earliest effect of spaceflight is an alteration in vestibular function due to microgravity.
Hypergravity exposure induced by centrifugation is also able to provoke motion sickness …

Gravity-sensitive cellular responses are regularly observed in both specialized and
nonspecialized cells. One potential mechanism for this sensitivity is a changing viscosity of …

Exposure to altered gravity influences cellular behaviour in cell cultures. Hydrogels are
amongst the most common materials used to produce tissue-engineering scaffolds, and their …

Cells sense and react on changes of the mechanical properties of their environment and,
likewise, respond to external mechanical stress applied to them. However, whether the …

Gravitational stress in general and microgravity (µg) in particular are regarded as major
stress factors responsible for immune system dysfunction in space. To assess the effects of …

The influence of microgravity and hypergravity on living systems has attracted significant
attention, but the use of these tools in tissue engineering (TE) remains relatively unexplored …

Gravity influences physical and biological processes, especially during development and
homeostasis of several tissues in the human body. Studies under altered gravity have been …

Microgravity (μg) is among the major stressors in space causing immune cell dysregulations.
These are frequently expressed as increased pro-inflammatory states of monocytes and …