Accelerating antibiotic discovery through artificial intelligence
MCR Melo, JRMA Maasch… - Communications …, 2021 - nature.com
By targeting invasive organisms, antibiotics insert themselves into the ancient struggle of the
host-pathogen evolutionary arms race. As pathogens evolve tactics for evading antibiotics …
host-pathogen evolutionary arms race. As pathogens evolve tactics for evading antibiotics …
Using genomics to track global antimicrobial resistance
RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
ResFinder–an open online resource for identification of antimicrobial resistance genes in next-generation sequencing data and prediction of phenotypes from …
Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …
The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities
Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …
Innovative and rapid antimicrobial susceptibility testing systems
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …
detection and quantification of resistance, combined with antimicrobial stewardship, are key …
Fighting antibiotic resistance in hospital-acquired infections: current state and emerging technologies in disease prevention, diagnostics and therapy
E Avershina, V Shapovalova, G Shipulin - Frontiers in microbiology, 2021 - frontiersin.org
Rising antibiotic resistance is a global threat that is projected to cause more deaths than all
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …
Genome-based prediction of bacterial antibiotic resistance
Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …
Machine learning for antimicrobial resistance prediction: current practice, limitations, and clinical perspective
Antimicrobial resistance (AMR) is a global health crisis that poses a great threat to modern
medicine. Effective prevention strategies are urgently required to slow the emergence and …
medicine. Effective prevention strategies are urgently required to slow the emergence and …
Correlation between Phenotypic and In Silico Detection of Antimicrobial Resistance in Salmonella enterica in Canada Using Staramr
Whole genome sequencing (WGS) of Salmonella supports both molecular typing and
detection of antimicrobial resistance (AMR). Here, we evaluated the correlation between …
detection of antimicrobial resistance (AMR). Here, we evaluated the correlation between …
Molecular architecture of early dissemination and massive second wave of the SARS-CoV-2 virus in a major metropolitan area
We sequenced the genomes of 5,085 severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strains causing two coronavirus disease 2019 (COVID-19) disease waves in …
(SARS-CoV-2) strains causing two coronavirus disease 2019 (COVID-19) disease waves in …