BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy among women
during reproductive age. PCOS is characterised by hyperandrogenaemia …

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility;
however, whether women with PCOS and spontaneous or drug-induced ovulatory cycles …

This review aimed to focus on the recent progress of the understanding of the role of
phosphatidylinositol 3-kinase (PI3K) in polycystic ovary syndrome (PCOS). In recent years, it …

STUDY QUESTION Does treatment with the insulin sensitizer metformin modify the levels
and activation of proteins related to the expression of the insulin-dependent glucose …

Background: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine/metabolic
disorder characterized by hyperandrogenemia and in most cases, by hyperinsulinemia in …

Embryo implantation is associated with an hypoxic endometrial microenvironment. Hypoxia‑
inducible factor‑1α (HIF‑1α) is activated under hypoxic conditions. In the present study, the …

Pregnancy loss is a frequent occurrence during the peri-implantation period, when there is
high glucose demand for embryonic development and endometrial decidualization. Glucose …

Accumulated evidence shows that vanin-1 (VNN1) plays a key part in glucose metabolism.
We explored the effect of VNN1 on cholesterol metabolism, inflammation, apoptosis in vitro …

Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic
hyperandrogenemia. Different evidence have shown that androgens could regulate the …