Alkenes and their derivatives are featured widely in a variety of natural products,
pharmaceuticals, and advanced materials. Significant efforts have been made toward the …

The activation of carbon–fluorine (C− F) bonds is an important topic in synthetic organic
chemistry. Metal‐mediated and‐catalyzed elimination of β‐or α‐fluorine proceeds under …

α-Trifluoromethylstyrene derivatives are versatile synthetic intermediates for the preparation
of more complex fluorinated compounds. Much attention has been paid to these compounds …

A concise and efficient hydrodefluorination process was developed for the synthesis of gem-
difluoroalkenes. This reaction employs rongalite as a masked proton source and does not …

C–F bond activation has drawn a lot of attention in the past, and the case of C (sp3)–F bonds
is particularly interesting as those are the strongest single bonds carbon makes with any …

A visible-light-promoted redox neutral γ, γ-difluoroallylation of cycloketone oxime ethers with
trifluoromethyl alkenes through C–C and C–F bond cleavage has been achieved, which …

Selective C− F bond functionalization of CF3 group represents an appealing strategy for the
incorporation of pharmaceutically privileged difluoromethylene moiety. Despite the recent …

Activation of the sp3 C− F bond in 2‐trifluoromethyl‐1‐alkenes was accomplished through
treatment with a Lewis acid. In the presence of an equimolar amount of EtAlCl2, the …

Monofluoroalkenes have found wide application in organic chemistry, medicinal chemistry,
and materials science. This review summarizes the most recent advances made regarding …

An efficient visible-light-promoted N-radical-mediated tandem radical cyclization/
defluorinated alkylation of β, γ-unsaturated hydrazones, and α-trifluoromethyl alkenes is …