Background: Parkinson's disease (PD) is a multi-symptom neurodegenerative disease
generally managed with medications, of which levodopa is the most effective. Determining …

The response to levodopa (LR) is important for managing Parkinson's Disease and is
measured with clinical scales prior to (OFF) and after (ON) levodopa. The aim of this study …

Parkinson's disease affects millions worldwide with a large rise in expected burden over the
coming decades. More easily accessible tools and techniques to diagnose and monitor …

Background Transcranial magnetic stimulation (TMS) can aid in alleviating clinical
symptoms in Parkinson's disease (PD). To better understand the neural mechanism of the …

While many studies focus on segmental variation in Parkinsonian speech, little is known
about prosodic modulations reflecting the ability to adapt to communicative demands in …

Background Deep brain stimulation (DBS) of globus pallidus interna (GPi) is an established
treatment for advanced Parkinson's disease (PD). However, in contrast to subthalamic …

Due to the marked interpersonal neuropathologic and clinical heterogeneity of Parkinson's
disease (PD), current interventions are not personalized and fail to benefit all patients …

Parkinson's disease (PD) has complex and multi-symptoms, making it challenging to detect
early-stage disease and to monitor the established patients. This also makes it challenging …

Background: Parkinson's disease (PD) is a progressive disorder with alterations in cortical
functional activity. Transcranial magnetic stimulation is known to incur motor benefits in PD …

Background Motor response to dopaminergic therapy is a characteristic of patients with
Parkinson's disease (PD). Whether nondopaminergic neurotransmitters contribute to …