The availability of a large amount of multiomics data enables data-driven discovery studies
on cancers. High-throughput data on mutations, gene/protein expression, immune scores …

Toxicogenomics measures molecular features, such as transcripts, proteins, metabolites and
epigenomic modifications, to understand and predict the toxicological effects of …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the …

The tumor immunosuppressive microenvironment (IME) significantly affects tumor
occurrence, progression, and prognosis, but the underlying molecular mechanisms remain …

The field of single-cell genomics is now observing a marked increase in the prevalence of
cohort-level studies that include hundreds of samples and feature complex designs. These …

Introduction People living with HIV (PLHIV) are characterized by functional reprogramming
of innate immune cells even after long-term antiretroviral therapy (ART). In order to assess …

Vitiligo is a complex disease wherein the environmental factors, in conjunction with the
underlying genetic predispositions, trigger the autoimmune destruction of melanocytes …

Antipsychotic drug (AP)-naïve first-episode psychosis (FEP) patients display premorbid
cognitive dysfunctions and dysglycemia. Brain insulin resistance may link metabolic and …

The overexpression of the ecotropic viral integration site-1 gene (EVI1/MECOM) marks the
most lethal acute myeloid leukemia (AML) subgroup carrying chromosome 3q26 …

RNA sequencing (RNA-seq) enables the accurate measurement of multiple transcriptomic
phenotypes for modeling the impacts of disease variants. Advances in technologies …