Simple Summary Ovarian cancer is a highly lethal female malignancy with high rates of
advanced stage and recurrent disease. Ovarian cancer is characterized as poorly …

Despite chemotherapy and surgical debulking options, ovarian cancer recurs and
disseminates frequently, with poor prognosis. However, the molecular mechanisms …

The chronic inflammation of tumor continues to recruit TAMs (tumor− associated
macrophages) to the TME (tumor microenvironment) and promote polarization. Pro …

Ovarian cancer is the leading cause of death in women with gynecological malignancy and
improvements in current treatments are needed. As with many other solid cancers, the …

Human plasmacytoid dendritic cells (pDCs) are crucially involved in the modulation of
adaptive T-cell responses in the course of neoplastic, viral, and autoimmune disorders. In …

Elevated levels of IL-10 in the microenvironment of human ovarian cancer and murine
models of ovarian cancer are well established and correlate with poor clinical prognosis …

The complex tumor microenvironment in gynecologic cancers plays a major role in
modulating anti-tumor immune responses. The interaction of cancer cells with the diverse …

Unlike other malignancies, ovarian cancer (OC) creates a complex tumor microenvironment
with distinctive peritoneal ascites consisting of a mixture of several immunosuppressive cells …

Background Alterations in the DNA methylation pattern are a hallmark of leukemias and
lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have …

Lung cancer, one of the leading causes of death worldwide, is often associated with a state
of immune suppression, but the molecular and functional basis remains enigmatic. Evidence …