Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Mitochondria are being recognized as key factors in many unexpected areas of biomedical
science. In addition to their well-known roles in oxidative phosphorylation and metabolism, it …

Mitochondria are multifaceted organelles with key roles in anabolic and catabolic
metabolism, bioenergetics, cellular signalling and nutrient sensing, and programmed cell …

Significance: Mitochondrial function is central to a wide range of biological processes in
health and disease and there is considerable interest in developing small molecules that are …

Patients with nonketotic hyperglycinemia and deficient glycine cleavage enzyme activity, but
without mutations in AMT, GLDC or GCSH, the genes encoding its constituent proteins …

The use of silver nanoparticles in food, food contact materials, dietary supplements and
cosmetics has increased significantly owing to their antibacterial and antifungal properties …

The mitochondria within human cells play a major role in a variety of critical processes
involved in cell survival and death. An understanding of mitochondrial involvement in …

Abstract Development of organ dysfunction associated with sepsis is now accepted to be
due at least in part to oxidative damage to mitochondria. Under normal circumstances …

Cancer is an ever-increasing problem that is yet to be harnessed. Frequent mutations make
this pathology very variable and, consequently, a considerable challenge. Intriguingly …

Overproduction of reactive oxygen species (ROS) under pathophysiologic conditions is part
of the disease process. These ROS are released from different sources, and in particular …