In physiological hemostasis a prompt recruitment of platelets on the vessel damage prevents
the bleeding by the rapid formation of a platelet plug. Qualitative and/or quantitative platelet …

Aspirin is integral to the secondary prevention of cardiovascular disease and acts to impair
the development of platelet-mediated atherothromboembolic events by irreversible inhibition …

The main function of platelets is to maintain normal hemostasis. Inefficient platelet
production and/or defective platelet function results in bleeding disorders resulting from a …

The contribution of platelets to normal hemostasis and vascular disease is well described.
However, recent studies make it clear that much remains to be learned about platelet …

Clopidogrel low-responsiveness assessed with multiple electrode platelet aggregometry
(MEA) has been shown to be a strong and independent predictor of early stent thrombosis …

Various antithrombotic agents are clinically used to inhibit the cascade of arterial or venous
thrombosis in cardiovascular diseases. Dual antiplatelet therapy with aspirin and P2Y 12 …

The majority of patients with platelet function disorders (PFD s) have normal platelet counts
and mild day‐to‐day bleeding symptoms, but are at risk of major hemorrhage at times of …

As the pathogenesis of arterial thrombosis often includes platelet thrombus formation (PTF),
antiplatelet agents are commonly used for the prevention of thromboembolic events. Here …

Platelets (PLTs), play a key role in hemostasis, clot stability and retraction as well as in
vascular repair and anti-microbial host defense. Upon vessel wall damage, PLTs undergo a …

Objectives: To develop reference ranges for platelet aggregation using the Multiplate
analyzer (Roche Diagnostics, Mannheim, Germany) in blood anticoagulated with sodium …