Selective crystallization via vibrational strong coupling

K Hirai, H Ishikawa, T Chervy, JA Hutchison… - Chemical science, 2021 - pubs.rsc.org
The coupling of (photo) chemical processes to optical cavity vacuum fields is an emerging
method for modulating molecular and material properties. Recent reports have shown that …

Combined experimental and theoretical studies of conformationally diverse (thio) semicarbazone-based semiconducting materials

A Panja, M Das, NC Jana, P Brandão, RM Gomila… - …, 2023 - pubs.rsc.org
This study reports the synthesis and characterization of two closely related semicarbazone/
thiosemicarbazone-based organic compounds: N-(2-hydroxy-3-methoxy-5 …

Heat capacities of selected active pharmaceutical ingredients

V Štejfa, V Pokorný, A Mathers, K Růžička… - The Journal of Chemical …, 2021 - Elsevier
Condensed-phase heat capacities of selected pharmaceutical active pharmaceutical
ingredients (APIs), namely (RS)-ibuprofen (CAS RN: 15687-27-1),(S)-ibuprofen (CAS RN …

Measuring the solubility of a quickly transforming metastable polymorph of carbamazepine

MA O'Mahony, DM Croker, ÅC Rasmuson… - … Process Research & …, 2013 - ACS Publications
The solubility of the stable FIII polymorph of the pharmaceutical compound carbamazepine
was measured by determining its solubility gravimetrically in ethanol and methanol. Where …

Application of phenyl-functionalized porous silica for the selective crystallization of carbamazepine metastable form II

J Ouyang, J Chen, W Chen, I Rosbottom… - Industrial & …, 2021 - ACS Publications
Polymorphic nucleation of carbamazepine (CBZ) in several solvents (ethanol, 2-propanol,
acetone, acetonitrile, toluene, and nitromethane) was investigated with different …

Electron properties of carbamazepine drug in form III

N El Hassan, A Ikni, JM Gillet… - Crystal growth & …, 2013 - ACS Publications
The experimental electron and electrostatic properties of carbamazepine drug molecule
(form III) were determined from accurate high-resolution X-ray diffraction data collected at …

Impact of rotamer diversity on the self-assembly of nearly isostructural molecular semiconductors

C McDowell, K Narayanaswamy, B Yadagiri… - Journal of Materials …, 2018 - pubs.rsc.org
Conformational diversity due to different orientations of structural subunits has a complex
impact on morphological disorder of organic semiconductors. Here, we isolate the impact of …

Understanding the planar conformations in diarylsubstituted heteroarenes: structural and theoretical insights

M Zia, S Hameed, A Frontera, E Irran, MM Naseer - CrystEngComm, 2021 - pubs.rsc.org
To access the applications of a conformationally flexible molecule, thorough understanding
of even the weak contributors to a particular conformation is necessary. We have …

Solid-state transformations of ribavirin as a result of high-shear mechanical processing

DM Vasa, PLD Wildfong - International Journal of Pharmaceutics, 2017 - Elsevier
Abstract Ribavirin (C 8 H 12 N 4 O 5; anti-viral agent) was crystallized as two unique, phase-
pure polymorphs (RI and R-II). Calorimetrically determined isobaric heat capacities and heat …

Solid form selection of highly solvating TAK-441 exhibiting solvate-trapping polymorphism

K Iwata, T Kojima, Y Ikeda - Crystal growth & design, 2014 - ACS Publications
Solid form selection of active pharmaceutical ingredients is essential for pharmaceutical
development. Solvates, except for hydrates, are rarely selected because of their physical …