When do co-infections matter?

AJ McArdle, A Turkova… - Current opinion in …, 2018 - journals.lww.com
When do co-infections matter? : Current Opinion in Infectious Diseases When do co-infections
matter? : Current Opinion in Infectious Diseases Log in or Register Subscribe to journalSubscribe …

The interaction of diabetes and tuberculosis: translating research to policy and practice

R van Crevel, JA Critchley - Tropical Medicine and Infectious Disease, 2021 - mdpi.com
Diabetes Mellitus increases the risk of developing Tuberculosis (TB) disease by about three
times; it also doubles the risk of death during TB treatment and other poor TB treatment …

Targeting immunometabolism in host defence against Mycobacterium tuberculosis

FJ Sheedy, M Divangahi - Immunology, 2021 - Wiley Online Library
In the face of ineffective vaccines, increasing antibiotic resistance and the decline in new
antibacterial drugs in the pipeline, tuberculosis (TB) still remains pandemic. Exposure to …

The knowns and unknowns of latent Mycobacterium tuberculosis infection

WH Boom, UE Schaible… - The Journal of clinical …, 2021 - Am Soc Clin Investig
Humans have been infected with Mycobacterium tuberculosis (Mtb) for thousands of years.
While tuberculosis (TB), one of the deadliest infectious diseases, is caused by uncontrolled …

The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois

AJ Udoakang, AL Djomkam Zune, K Tapela… - Frontiers in …, 2023 - frontiersin.org
In December 2019, a novel pneumonic condition, Coronavirus disease 2019 (COVID-19)
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in …

A Review of the development of multitarget molecules against HIV-TB coinfection pathogens

DI Leite, S de Castro Bazan Moura… - Molecules, 2023 - mdpi.com
The human immunodeficiency virus (HIV) produces the pathologic basis of acquired
immunodeficiency syndrome (AIDS). An increase in the viral load in the body leads to a …

[HTML][HTML] Unmasking the hidden impact of viruses on tuberculosis risk

F Darboe, JF Reijneveld, DP Maison, L Martinez… - Trends in …, 2024 - cell.com
Tuberculosis (TB) is a leading cause of mortality from an infectious disease. In this opinion
article, we focus on accumulating scientific evidence indicating that viral infections may …

[HTML][HTML] Plasma host protein biomarkers correlating with increasing Mycobacterium tuberculosis infection activity prior to tuberculosis diagnosis in people living with …

SN Singer, OC Ndumnego, RS Kim, T Ndung'u… - …, 2022 - thelancet.com
Summary Background Biomarkers correlating with Mycobacterium tuberculosis infection
activity/burden in asymptomatic individuals are urgently needed to identify and treat those at …

[HTML][HTML] Novel serological biomarker panel using protein microarray can distinguish active TB from latent TB infection

J Li, Y Wang, L Yan, C Zhang, Y He, J Zou, Y Zhou… - Microbes and …, 2022 - Elsevier
Background Rapid laboratory technologies which can effectively distinguish active
tuberculosis (ATB) from controls and latent tuberculosis infection (LTBI) are lacked. The …

Beyond Killing Mycobacterium tuberculosis: Disease Tolerance

M Divangahi, N Khan, E Kaufmann - Frontiers in immunology, 2018 - frontiersin.org
Host defense strategies against infectious diseases are comprised of both host resistance
and disease tolerance. Resistance is the ability of the host to prevent invasion or to eliminate …