In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

The role of the maternal immune system in reproductive success in humans remains
controversial. Here we focus on the events that occur in the maternal decidua during the first …

Avoiding destruction by immune cells is a hallmark of cancer, yet how tumors ultimately
evade control by natural killer (NK) cells remains incompletely defined. Using global …

Innate lymphoid cells (ILCs) are effectors and regulators of innate immunity and tissue
modeling and repair. Researchers have identified subsets of ILCs with differing functional …

Although the function of the circulating immune cell compartment has been studied in detail
for decades, limitations in terms of access and cell yields from peripheral tissues have …

Natural killer (NK) cells are present in large populations at the maternal-fetal interface during
early pregnancy. However, the role of NK cells in fetal growth is unclear. Here, we have …

Tissue health is dictated by the capacity to respond to perturbations and then return to
homeostasis. Mechanisms that initiate, maintain, and regulate immune responses in tissues …

The female reproductive tract harbors distinct microbial communities, as in the vagina,
cervical canal, uterus, and fallopian tubes. The nature of the vaginal microbiota is well …

The multifaceted organization of the immune system involves not only patrolling
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …

Our understanding of development and function of natural killer (NK) cells has progressed
significantly in recent years. However, exactly how uterine NK (uNK) cells develop and …