The safety and toxicity of phage therapy: a review of animal and clinical studies

D Liu, JD Van Belleghem, CR de Vries, E Burgener… - Viruses, 2021 - mdpi.com
Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of
interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and …

Prebiotics, probiotics, synbiotics, paraprobiotics and postbiotic compounds in IBD

A Martyniak, A Medyńska-Przęczek, A Wędrychowicz… - Biomolecules, 2021 - mdpi.com
The increasing incidence of inflammatory bowel diseases (IBD) and the increasing severity
of the course of these diseases create the need for developing new methods of therapy. The …

Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

[HTML][HTML] Gram-positive bacterial cell envelopes: The impact on the activity of antimicrobial peptides

N Malanovic, K Lohner - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
A number of cationic antimicrobial peptides, effectors of innate immunity, are supposed to
act at the cytoplasmic membrane leading to permeabilization and eventually membrane …

Polysaccharide degradation by the intestinal microbiota and its influence on human health and disease

DW Cockburn, NM Koropatkin - Journal of molecular biology, 2016 - Elsevier
Carbohydrates comprise a large fraction of the typical diet, yet humans are only able to
directly process some types of starch and simple sugars. The remainder transits the large …

Antimicrobial peptides targeting gram-positive bacteria

N Malanovic, K Lohner - Pharmaceuticals, 2016 - mdpi.com
Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …

Bacterial cell mechanics

GK Auer, DB Weibel - Biochemistry, 2017 - ACS Publications
Cellular mechanical properties play an integral role in bacterial survival and adaptation.
Historically, the bacterial cell wall and, in particular, the layer of polymeric material called the …

Envelope structures of Gram-positive bacteria

M Rajagopal, S Walker - Protein and sugar export and assembly in Gram …, 2017 - Springer
Gram-positive organisms, including the pathogens Staphylococcus aureus, Streptococcus
pneumoniae, and Enterococcus faecalis, have dynamic cell envelopes that mediate …

Surfactants as antimicrobials: a brief overview of microbial interfacial chemistry and surfactant antimicrobial activity

NA Falk - Journal of Surfactants and Detergents, 2019 - Wiley Online Library
In this brief overview of a large and complex subject, as presented at the 2018 Surfactants in
Solution conference, the need for, and impact of, hard surface antimicrobial products is …

Enzymes and mechanisms employed by tailed bacteriophages to breach the bacterial cell barriers

S Fernandes, C São-José - Viruses, 2018 - mdpi.com
Monoderm bacteria possess a cell envelope made of a cytoplasmic membrane and a cell
wall, whereas diderm bacteria have and extra lipid layer, the outer membrane, covering the …