Senescence is a cellular response to a variety of stress signals that is characterized by a
stable withdrawal from the cell cycle and major changes in cell morphology and physiology …

Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …

Radiation therapy (RT) is responsible for at least 40% of cancer cures, however treatment
resistance remains a clinical problem. There have been recent advances in understanding …

Globally, 50 million people live with dementia, with Alzheimer disease (AD) being
responsible for two-thirds of the total cases. As ageing is the main risk factor for dementia …

Cellular senescence, a process that imposes permanent proliferative arrest on cells in
response to various stressors, has emerged as a potentially important contributor to aging …

Ageing is a major risk factor for developing many neurodegenerative diseases. Cellular
senescence is a homeostatic biological process that has a key role in driving ageing. There …

Cellular theory of aging states that human aging is the result of cellular aging, in which an
increasing proportion of cells reach senescence. Senescence, from the Latin word senex …

The past 20 years have seen dramatic changes in the delivery of radiation therapy, but the
impact of radiobiology on the clinic has been far less substantial. A major consideration in …

The purpose of this study was to examine the association between socioeconomic status
(SES) and leukocyte telomere length (LTL)–a marker of cell aging that has been linked to …

Ionizing radiation (IR), such as X-rays and gamma (γ)-rays, mediates various forms of cancer
cell death such as apoptosis, necrosis, autophagy, mitotic catastrophe, and senescence …