Background Completed suicide is a major cause of death in bipolar disorder (BD) patients.
Objective The aim of this paper is to provide an overall review of the existing literature of …

Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …

Current literature on the effects of chronic stress in general health converges to the concept
of allostatic load (AL). AL is the bodily 'wear and tear'that emerges with sustained allostatic …

BackgroundAnecdotal and biographical reports suggest that bipolar disorder may be
associated with high IQ or creativity, but evidence for any such connection is weak. AimsTo …

A number of lines of converging evidence suggest that brain-derived neurotrophic factor
(BDNF) may play a role in the onset and treatment of bipolar disorder. We review pertinent …

Objective: The singular phenomenon of switching from depression to its opposite state of
mania or hypomania, and vice versa, distinguishes bipolar disorder from all other psychiatric …

The cognitive impairment and neuroanatomical changes that takes place among patients
with bipolar disorder (BD) patients has been well described. Recent data suggest that …

Bipolar disorder (BP) is a complex disorder caused by a number of liability genes interacting
with the environment. In recent years, a large number of linkage and association studies …

Objective: The long-term course of bipolar disorder is typified by recurring mood episodes of
opposite polarity as well as mixed states. Rapid-cycling bipolar disorder refers to the …

BackgroundAllostatic load (AL) relates to the neural and bodily “wear and tear” that emerge
in the context of chronic stress. This paper aims to provide clinicians with a comprehensive …