Gene expression tradeoffs determine bacterial survival and adaptation to antibiotic stress

JC Kratz, S Banerjee - PRX Life, 2024 - APS
To optimize their fitness, cells face the crucial task of efficiently responding to various
stresses. This necessitates striking a balance between conserving resources for survival and …

Antibiotic-mediated microbial community restructuring is dictated by variability in antibiotic susceptibility and population interactions

K Kim, A Weiss, HR Ma, HI Son, Z Zhou, L You - bioRxiv, 2024 - biorxiv.org
It is widely known that faster-growing bacterial cells are more susceptible to antibiotics.
Given this notion, it appears intuitive that antibiotic treatment would enrich slower-growing …

Gradual entry into carbon starvation decreases the death rate of Escherichia coli

R Droghetti, Z Gough, H Allaei, S Schink, U Gerland - bioRxiv, 2024 - biorxiv.org
Bacterial fitness is determined both by how fast cells grow in nutrient-rich environments and
by how well they survive when nutrients are depleted. However, these behaviors are not …

Antibiotics change the growth rate heterogeneity and morphology of bacteria

M Kals, E Kals, J Kotar, A Donald, L Mancini, P Cicuta - bioRxiv, 2024 - biorxiv.org
A better understanding of the system-level effects of antibiotics is necessary to fight the rise
of antibiotic resistance. Utilising the Multipad Agarose Plate (MAP), we monitor the growth …