Management of motion and anatomical variations in charged particle therapy: past, present, and into the future

JM Pakela, A Knopf, L Dong, A Rucinski… - Frontiers in …, 2022 - frontiersin.org
The major aim of radiation therapy is to provide curative or palliative treatment to cancerous
malignancies while minimizing damage to healthy tissues. Charged particle radiotherapy …

Fast Monte Carlo dose calculation in proton therapy

J Holmes, H Feng, L Zhang, MK Fix… - Physics in Medicine & …, 2024 - iopscience.iop.org
This article examines the critical role of fast Monte Carlo (MC) dose calculations in
advancing proton therapy techniques, particularly in the context of increasing treatment …

PyMedPhys: A community effort to develop an open, Python-based standard library for medical physics applications

S Biggs, M Jennings, S Swerdloff, P Chlap… - Journal of Open …, 2022 - joss.theoj.org
PyMedPhys is an open-source medical physics library built for Python by a diverse
community that values and prioritizes code sharing, review, continuous improvement, and …

Clinical validation of a GPU-based Monte Carlo dose engine of a commercial treatment planning system for pencil beam scanning proton therapy

F Fracchiolla, E Engwall, M Janson, F Tamm… - Physica Medica, 2021 - Elsevier
Purpose To perform the validation of the GPU-based (Graphical Processing Unit based)
proton Monte Carlo (MC) dose engine implemented in a commercial TPS (RayStation 10B) …

Millisecond speed deep learning based proton dose calculation with Monte Carlo accuracy

O Pastor-Serrano, Z Perkó - Physics in Medicine & Biology, 2022 - iopscience.iop.org
Objective. Next generation online and real-time adaptive radiotherapy workflows require
precise particle transport simulations in sub-second times, which is unfeasible with current …

Detection of range shifts in proton beam therapy using the J-PET scanner: a patient simulation study

K Brzeziński, J Baran, D Borys… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. The Jagiellonian positron emission tomography (J-PET) technology, based on
plastic scintillators, has been proposed as a cost effective tool for detecting range deviations …

Development and benchmarking of a Monte Carlo dose engine for proton radiation therapy

P Lysakovski, A Ferrari, T Tessonnier, J Besuglow… - Frontiers in …, 2021 - frontiersin.org
Dose calculation algorithms based on Monte Carlo (MC) simulations play a crucial role in
radiotherapy. Here, the development and benchmarking of a novel MC dose engine …

An optimized framework for cone‐beam computed tomography‐based online evaluation for proton therapy

CW Chang, R Nilsson, S Andersson… - Medical …, 2023 - Wiley Online Library
Background Clinical evidence has demonstrated that proton therapy can achieve
comparable tumor control probabilities compared to conventional photon therapy but with …

Single proton LET characterization with the Timepix detector and artificial intelligence for advanced proton therapy treatment planning

P Stasica, H Nguyen, C Granja, R Kopeć… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Protons have advantageous dose distributions and are increasingly used in
cancer therapy. At the depth of the Bragg peak range, protons produce a mixed radiation …

MOQUI: an open-source GPU-based Monte Carlo code for proton dose calculation with efficient data structure

H Lee, J Shin, JM Verburg, M Bobić… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. Monte Carlo (MC) codes are increasingly used for accurate radiotherapy dose
calculation. In proton therapy, the accuracy of the dose calculation algorithm is expected to …