Applications of vibrational spectroscopy for analysis of connective tissues

W Querido, S Kandel, N Pleshko - Molecules, 2021 - mdpi.com
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Fundamental developments in infrared spectroscopic imaging for biomedical applications

M Pilling, P Gardner - Chemical Society reviews, 2016 - pubs.rsc.org
Infrared chemical imaging is a rapidly emerging field with new advances in instrumentation,
data acquisition and data analysis. These developments have had significant impact in …

Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences

TP Wrobel, R Bhargava - Analytical chemistry, 2018 - ACS Publications
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …

Aluminium foil as a potential substrate for ATR-FTIR, transflection FTIR or Raman spectrochemical analysis of biological specimens

L Cui, HJ Butler, PL Martin-Hirsch, FL Martin - Analytical methods, 2016 - pubs.rsc.org
The substantial cost of substrates is an enormous obstacle in the successful translation of
biospectroscopy (IR or Raman) into routine clinical/laboratory practice (screening or …

Rapid detection of serological biomarkers in gallbladder carcinoma using fourier transform infrared spectroscopy combined with machine learning

J Dou, W Dawuti, J Li, H Zhao, R Zhou, J Zhou, R Lin… - Talanta, 2023 - Elsevier
Gallbladder cancer (GBC) is the most common malignant tumour of the biliary tract. GBC is
difficult to diagnose and treat at an early stage because of the lack of effective serum …

[HTML][HTML] Shining a light on clinical spectroscopy: Translation of diagnostic IR, 2D-IR and Raman spectroscopy towards the clinic

HJ Butler, JM Cameron, CA Jenkins, G Hithell… - Clinical …, 2019 - Elsevier
In recent years, the application of vibrational spectroscopy in biomedical research has
rapidly expanded; covering aspects of pharmaceutical development, to point-of-care …

Vibrational spectroscopic analysis and quantification of proteins in human blood plasma and serum

JM Cameron, C Bruno, DR Parachalil, MJ Baker… - … Spectroscopy in Protein …, 2020 - Elsevier
Alterations in biomolecular components in human blood are commonly used as an
indication of disease states, namely differences in protein concentration. Unfortunately …

High-throughput quantum cascade laser (QCL) spectral histopathology: a practical approach towards clinical translation

MJ Pilling, A Henderson, B Bird, MD Brown… - Faraday …, 2016 - pubs.rsc.org
Infrared microscopy has become one of the key techniques in the biomedical research field
for interrogating tissue. In partnership with multivariate analysis and machine learning …

Single-cell analysis using Fourier transform infrared microspectroscopy

J Doherty, G Cinque, P Gardner - Applied Spectroscopy Reviews, 2017 - Taylor & Francis
Fourier transform infrared spectroscopy (FTIR) is a well-established, non-destructive method
of obtaining chemical information from biological samples such as tissues and cells. This …

Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer's disease

M Paraskevaidi, CLM Morais, DLD Freitas, KMG Lima… - Analyst, 2018 - pubs.rsc.org
Alzheimer's disease (AD) is currently under-diagnosed and is predicted to affect a great
number of people in the future, due to the unrestrained aging of the population. An accurate …