CMV is an ancient herpesvirus that has co-evolved with its host over millions of years. The
236 kbp genome encodes at least 165 genes, four non-coding RNAs and 14 miRNAs. Of the …

Background: Reactivation of CMV from latency results in serious morbidity and mortality in
immunocompromised transplant recipients. The mechanism by which CMV reactivates from …

Cytomegalovirus (CMV) infection is a common infection in adults (seropositive 60–99%
globally), and is associated with cardiovascular diseases, in line with risk factors such as …

Intranasal infection of mice with the murine γ-herpesvirus MHV-68 results in an acute lytic
infection in the lung, followed by the establishment of lifelong latency. Development of an …

ABSTRACT B cells have previously been identified as the major hematopoietic cell type
harboring latent gammaherpesvirus 68 (γHV68)(NP Sunil-Chandra, S. Efstathiou, and AA …

Several low-grade persistent viral infections induce and sustain very large numbers of virus-
specific effector T cells. This was first described as a response to cytomegalovirus (CMV), a …

To define immune mechanisms that regulate chronic and latent herpesvirus infection, we
analyzed the role of interferon γ (IFN-γ) during murine cytomegalovirus (MCMV) infection …

During murine cytomegalovirus (mCMV) latency in the lungs, most of the viral genomes are
transcriptionally silent at the major immediate-early locus, but rare and stochastic episodes …

Sexually transmitted diseases, genital ulcer disease, and progesterone therapy increase
susceptibility to lentivirus transmission. Infection of cells by human immunodeficiency virus …

Ever since the discovery of blood types early in the last century, transfusion medicine has
evolved at a breakneck pace. This second edition of Blood Banking and Transfusion …