Radiotherapy (RT) is used to treat approximately 80% of patients with cancer of the head
and neck. Despite enormous advances in RT planning and delivery, a significant number of …

Most new radiation techniques, have been introduced primarily to reduce the dose to normal
tissues in order to prevent radiation-induced side effects. Radiotherapy with protons is such …

Background and purpose A comprehensive individual toxicity risk profile is needed to
improve radiation treatment optimisation, minimising toxicity burden, in head and neck …

In the Netherlands, the model-based approach is used to identify patients with head and
neck cancer who may benefit most from proton therapy in terms of prevention of late …

Background Head and neck cancer (HNC) and its therapy are associated with acute and
late swallowing dysfunction. Consensus guidelines regarding evaluation and management …

Abstract Purpose In the Netherlands, head and neck cancer (HNC) patients qualify for
intensity modulated proton therapy (IMPT) based on model-based selection (MBS). The aim …

Radiotherapy (radiation therapy) is one of the main treatments for cancer. The aim is to
deliver a prescribed radiation dose to the tumor, while keeping the unavoidable dose to the …

Background and purpose Current models for the prediction of late patient-rated moderate-to-
severe xerostomia (XER 12m) and sticky saliva (STIC 12m) after radiotherapy are based on …

Background Treatment plan quality assurance (QA) is important for clinical studies and for
institutions aiming to generate near-optimal individualized treatment plans. However …

Increasingly, squamous cell carcinoma of the oropharynx (OPSCC) is attributable to
transformation resulting from high-risk human papillomavirus (HPV) infection. Such cancers …